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通过脑磁图测量定位癫痫样病灶。

Localization of epileptiform foci by means of MEG measurements.

作者信息

Anogianakis G, Anninos P A

机构信息

Department of Physiology, Faculty of Medicine, University of Thessaloniki, Greece.

出版信息

Int J Neurosci. 1988 Jan;38(1-2):141-9. doi: 10.3109/00207458809000493.

DOI:10.3109/00207458809000493
PMID:3356498
Abstract

Systematic studies of the magnetoencephalogram (MEG) in normal and pathological subjects (mainly with focal epilepsies) showed that the MEG may evidence significant brain activities even if they are not identifiable in the electroencephalogram (EEG). They also showed that the MEG has a considerably higher spatial resolution than the EEG. A two-dimensional mapping technique was used to get such a representation of the data that would enable the investigator to draw his conclusions mainly from inspecting the plots. The technique is characterized by an isospectral synchronized power (iso-SSP) mapping of the scalp distribution of specified frequency bands of the MEG power spectrum. In this way the precise projection on the scalp of an epileptiform focus can be determined without applying a strong eliciting stimulus or relying on the analysis of the simultaneously recorded EEG. Our results compare very favourably with the clinical picture of our pathological subjects.

摘要

对正常和病理受试者(主要是局灶性癫痫患者)的脑磁图(MEG)进行的系统研究表明,即使在脑电图(EEG)中无法识别,MEG也可能显示出显著的脑活动。研究还表明,MEG的空间分辨率比EEG高得多。使用二维映射技术来获取数据的这种表示形式,使研究人员能够主要通过检查图表得出结论。该技术的特点是对MEG功率谱特定频段的头皮分布进行等谱同步功率(iso-SSP)映射。通过这种方式,无需施加强烈的诱发刺激或依赖于对同时记录的EEG进行分析,就可以确定癫痫样病灶在头皮上的精确投影。我们的结果与病理受试者的临床表现非常吻合。

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