Tsereteli Tamar, Chong Erica, Louie Karmen, Bokhua Zaza, Winikoff Beverly
a Gynuity Health Projects , Tbilisi , Georgia ;
b Gynuity Health Projects , New York , NY , USA ;
Eur J Contracept Reprod Health Care. 2016 Oct;21(5):367-71. doi: 10.1080/13625187.2016.1211632. Epub 2016 Jul 22.
The aim of the study was to examine the acceptability and feasibility of early medical abortion using 200 mg mifepristone and 400 μg buccal misoprostol in Georgia, outside the capital city of Tbilisi.
A total of 622 women in four regions of western and eastern Georgia who presented for termination of pregnancy at up to 63 d of gestation were enrolled in the study. In the western regions, women took one 200 mg pill of mifepristone in the clinic and were given the option of administering 400 μg misoprostol buccally, either at the clinic or at home, 24-48 h later. In the eastern region, women were given the option to take both drugs at home. Abortion status was determined 2 weeks after mifepristone administration.
Ninety-five percent of participants had a successful abortion. Twenty-one percent of women in the eastern region elected to take mifepristone at home; nearly all participants in both regions (98%) chose to take misoprostol at home. Ninety-five percent of women were very satisfied or satisfied with the method, and 95% said they would prefer medical abortion for a future procedure.
Medical abortion with mifepristone and 400 μg buccal misoprostol is an acceptable and feasible option for women in Georgia, outside the capital city of Tbilisi.
本研究旨在探讨在格鲁吉亚第比利斯市以外地区使用200毫克米非司酮和400微克口腔用米索前列醇进行早期药物流产的可接受性和可行性。
共有622名来自格鲁吉亚西部和东部四个地区、妊娠天数达63天前来终止妊娠的妇女参与了本研究。在西部地区，妇女在诊所服用一片200毫克的米非司酮，并可选择在24至48小时后于诊所或家中口腔含服400微克米索前列醇。在东部地区，妇女可选择在家中服用两种药物。在服用米非司酮两周后确定流产情况。
95%的参与者流产成功。东部地区21%的妇女选择在家中服用米非司酮；两个地区几乎所有参与者（98%）都选择在家中服用米索前列醇。95%的妇女对该方法非常满意或满意，95%的妇女表示未来若需流产更倾向于选择药物流产。
对于格鲁吉亚第比利斯市以外地区的妇女而言，使用米非司酮和400微克口腔用米索前列醇进行药物流产是一种可接受且可行的选择。
