Nakada T, Furuta H, Koike H, Katayama T, Teranishi H
Department of Urology, Faculty of Medicine, Toyama Medical and Pharmaceutical University, Japan.
Int Urol Nephrol. 1989;21(2):201-9. doi: 10.1007/BF02550809.
A case of Itai-itai (ouch-ouch) disease with reduced urinary kallikrein excretion and slightly enhanced renin-angiotensin-aldosterone system is described. Although it is well known that cadmium toxicity frequently affects the renal tubular lesions, this report is the first to demonstrate the impaired urine concentrating ability in this disease.
本文描述了一例痛痛病患者，其尿激肽释放酶排泄减少，肾素-血管紧张素-醛固酮系统略有增强。虽然镉中毒常影响肾小管病变已广为人知，但本报告首次证实了该病患者尿液浓缩能力受损。
