Brancato R, Pratesi R, Leoni G, Trabucchi G, Vanni U
Department of Ophthalmology, S. Raffaele Hospital, University of Milan, Italy.
Invest Ophthalmol Vis Sci. 1989 Jul;30(7):1504-10.
Argon lasers are the most frequently used laser source for retinal photocoagulation. These are expensive, bulky and low-efficiency devices. In contrast, diode semiconductor lasers have a number of characteristics that make them attractive for medical application: compact size, high electrical-to-optical efficiency, and long operating lifetime. Comparable irradiance lesions (about 120 Wcm2), ophthalmoscopically similar to those obtained therapeutically in humans, were obtained by a diode and an argon laser. Twenty-four hours after the treatment, a study of these lesions was made by light and electron microscopy. Argon irradiations resulted in damage to both the inner and the outer retinal layers, while the diode laser radiation produced damage to the outer retina and choroid. A sufficient diode laser light passed into the choroid to induce small vessel occlusions and/or edema. The histological characteristics of the lesions produced by the two lasers suggest the use of the diode lasers, as well as argon lasers, in the treatment of retinal and subretinal pathologies.
氩激光是视网膜光凝最常用的激光源。这些设备价格昂贵、体积庞大且效率低下。相比之下，二极管半导体激光器具有许多使其在医疗应用中具有吸引力的特性：尺寸紧凑、电光效率高以及工作寿命长。通过二极管激光器和氩激光获得了可比的辐照度损伤（约120W/cm²），在检眼镜下与在人类治疗中获得的损伤相似。治疗24小时后，通过光学显微镜和电子显微镜对这些损伤进行了研究。氩激光照射导致视网膜内层和外层均受损，而二极管激光辐射则导致外层视网膜和脉络膜受损。足够的二极管激光进入脉络膜以诱导小血管闭塞和/或水肿。两种激光产生的损伤的组织学特征表明，二极管激光器以及氩激光器可用于治疗视网膜和视网膜下病变。
