Koffarnus Mikhail N, Johnson Matthew W, Thompson-Lake Daisy G Y, Wesley Michael J, Lohrenz Terry, Montague P Read, Bickel Warren K
Virginia Tech Carilion Research Institute, Virginia Tech.
Behavioral Pharmacology Research Unit, School of Medicine, Johns Hopkins University.
Exp Clin Psychopharmacol. 2016 Aug;24(4):297-304. doi: 10.1037/pha0000080.
Cocaine users have a higher incidence of risky sexual behavior and HIV infection than nonusers. Our aim was to measure whether safer sex discount rates-a measure of the likelihood of having immediate unprotected sex versus waiting to have safer sex-differed between controls and cocaine users of varying severity. Of the 162 individuals included in the primary data analyses, 69 met the Diagnostic and Statistical Manual of Mental Disorders (4th ed., text rev.; DSM-IV-TR) criteria for cocaine dependence, 29 were recreational cocaine users who did not meet the dependence criteria, and 64 were controls. Participants completed the Sexual Discounting Task, which measures a person's likelihood of using a condom when one is immediately available and how that likelihood decreases as a function of delay to condom availability with regard to 4 images chosen by the participants of hypothetical sexual partners differing in perceived desirability and likelihood of having a sexually transmitted infection. When a condom was immediately available, the stated likelihood of condom use sometimes differed between cocaine users and controls, which depended on the image condition. Even after controlling for rates of condom use when one is immediately available, the cocaine-dependent and recreational users groups were more sensitive to delay to condom availability than controls. Safer sex discount rates were also related to intelligence scores. The Sexual Discounting Task identifies delay as a key variable that impacts the likelihood of using a condom among these groups and suggests that HIV prevention efforts may be differentially effective based on an individual's safer sex discount rate. (PsycINFO Database Record
可卡因使用者比非使用者有更高的危险性行为发生率和艾滋病毒感染率。我们的目的是测量安全性行为折扣率(一种衡量立即进行无保护性行为与等待进行安全性行为可能性的指标)在不同严重程度的可卡因使用者和对照组之间是否存在差异。在纳入主要数据分析的162名个体中,69名符合《精神疾病诊断与统计手册》(第4版,文本修订版;DSM-IV-TR)中可卡因依赖的标准,29名是不符合依赖标准的消遣性可卡因使用者,64名是对照组。参与者完成了性折扣任务,该任务测量了在有避孕套立即可用时使用避孕套的可能性,以及随着避孕套延迟可用,这种可能性如何根据参与者选择的4张假设性伴侣的图片而降低,这些伴侣在感知吸引力和感染性传播感染的可能性方面有所不同。当避孕套立即可用时,可卡因使用者和对照组之间使用避孕套的既定可能性有时会有所不同,这取决于图片条件。即使在控制了有避孕套立即可用时的使用率之后,可卡因依赖组和消遣性使用者组比对照组对避孕套延迟可用更敏感。安全性行为折扣率也与智力得分有关。性折扣任务确定延迟是影响这些群体中使用避孕套可能性的关键变量,并表明基于个体的安全性行为折扣率,艾滋病毒预防努力可能会有不同的效果。(PsycINFO数据库记录)