Gessner D K, Ringseis R, Eder K
Institute of Animal Nutrition and Nutrition Physiology, Justus-Liebig-University Giessen, Giessen, Germany.
J Anim Physiol Anim Nutr (Berl). 2017 Aug;101(4):605-628. doi: 10.1111/jpn.12579. Epub 2016 Jul 25.
Polyphenols are secondary plant metabolites which have been shown to exert antioxidative and antiinflamma tory effects in cell culture, rodent and human studies. Based on the fact that conditions of oxidative stress and inflammation are highly relevant in farm animals, polyphenols are considered as promising feed additives in the nutrition of farm animals. However, in contrast to many studies existing with model animals and humans, potential antioxidative and antiinflammatory effects of polyphenols have been less investigated in farm animals so far. This review aims to give an overview about potential antioxidative and antiinflammatory effects in farm animals. The first part of the review highlights the occurrence and the consequences of oxidative stress and inflammation on animal health and performance. The second part of the review deals with bioavailability and metabolism of polyphenols in farm animals. The third and main part of the review presents an overview of the findings from studies which investigated the effects of polyphenols of various plant sources in pigs, poultry and cattle, with particular consideration of effects on the antioxidant system and inflammation.
多酚是植物的次生代谢产物，在细胞培养、啮齿动物和人体研究中已显示出具有抗氧化和抗炎作用。鉴于氧化应激和炎症状况与农场动物高度相关，多酚被认为是农场动物营养中很有前景的饲料添加剂。然而，与许多针对模式动物和人类的现有研究相比，到目前为止，多酚在农场动物中的潜在抗氧化和抗炎作用研究较少。这篇综述旨在概述多酚在农场动物中的潜在抗氧化和抗炎作用。综述的第一部分重点介绍氧化应激和炎症对动物健康和生产性能的发生情况及影响。综述的第二部分探讨了多酚在农场动物中的生物利用度和代谢情况。综述的第三部分也是主要部分，概述了研究各种植物来源的多酚对猪、家禽和牛的影响的研究结果，特别考虑了对抗氧化系统和炎症的影响。
