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无支架和有支架主动脉瓣生物假体存在时主动脉根部应力的计算比较。

Computational comparison of aortic root stresses in presence of stentless and stented aortic valve bio-prostheses.

作者信息

Nestola M G C, Faggiano E, Vergara C, Lancellotti R M, Ippolito S, Antona C, Filippi S, Quarteroni A, Scrofani R

机构信息

a Faculty of Informatics, Institute of Computational Science (ICS) , University of Lugano , Lugano , Switzerland .

g Dipartimento di Ingegneria, Nonlinear Physics and Mathematical Modeling Lab , Università Campus Bio-Medico di Roma , Rome , Italy .

出版信息

Comput Methods Biomech Biomed Engin. 2017 Feb;20(2):171-181. doi: 10.1080/10255842.2016.1207171. Epub 2016 Jul 26.

Abstract

We provide a computational comparison of the performance of stentless and stented aortic prostheses, in terms of aortic root displacements and internal stresses. To this aim, we consider three real patients; for each of them, we draw the two prostheses configurations, which are characterized by different mechanical properties and we also consider the native configuration. For each of these scenarios, we solve the fluid-structure interaction problem arising between blood and aortic root, through Finite Elements. In particular, the Arbitrary Lagrangian-Eulerian formulation is used for the numerical solution of the fluid-dynamic equations and a hyperelastic material model is adopted to predict the mechanical response of the aortic wall and the two prostheses. The computational results are analyzed in terms of aortic flow, internal wall stresses and aortic wall/prosthesis displacements; a quantitative comparison of the mechanical behavior of the three scenarios is reported. The numerical results highlight a good agreement between stentless and native displacements and internal wall stresses, whereas higher/non-physiological stresses are found for the stented case.

摘要

我们根据主动脉根部位移和内部应力,对无支架和有支架主动脉假体的性能进行了计算比较。为此,我们考虑了三名真实患者;对于他们中的每一个,我们绘制了两种假体配置,其具有不同的力学性能,并且我们还考虑了天然配置。对于这些情况中的每一种,我们通过有限元法解决血液与主动脉根部之间出现的流固耦合问题。特别是,任意拉格朗日 - 欧拉公式用于流体动力学方程的数值解,并采用超弹性材料模型来预测主动脉壁和两种假体的力学响应。根据主动脉血流、内壁应力和主动脉壁/假体位移对计算结果进行分析;报告了三种情况力学行为的定量比较。数值结果表明无支架和天然状态下的位移及内壁应力之间有良好的一致性,而有支架情况下发现有更高/非生理性应力。

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