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Deeper Than the Epithelium: Role of Matrix and Fibroblasts in Pediatric and Adult Eosinophilic Esophagitis.

作者信息

Nguyen Nathalie, Furuta Glenn T, Masterson Joanne C

机构信息

Digestive Health Institute, Section of Pediatric Gastroenterology, Hepatology and Nutrition, Children's Hospital Colorado, Gastrointestinal Eosinophilic Diseases Program, Department of Pediatrics, Mucosal Inflammation Program, University of Colorado School of Medicine, Aurora.

出版信息

J Pediatr Gastroenterol Nutr. 2016 Aug;63(2):168-9. doi: 10.1097/MPG.0000000000001183.

DOI:10.1097/MPG.0000000000001183
PMID:27457777
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4965178/
Abstract
摘要

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引用本文的文献

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Type 2 Inflammation in Eosinophilic Esophagitis: From Pathophysiology to Therapeutic Targets.嗜酸性食管炎中的2型炎症:从病理生理学到治疗靶点
Front Physiol. 2022 Jan 12;12:815842. doi: 10.3389/fphys.2021.815842. eCollection 2021.
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Creating a multi-center rare disease consortium - the Consortium of Eosinophilic Gastrointestinal Disease Researchers (CEGIR).创建一个多中心罕见病联盟——嗜酸性胃肠道疾病研究人员联盟(CEGIR)。
Transl Sci Rare Dis. 2017 Dec 18;2(3-4):141-155. doi: 10.3233/TRD-170016.

本文引用的文献

1
Rigid substrate induces esophageal smooth muscle hypertrophy and eosinophilic esophagitis fibrotic gene expression.刚性底物诱导食管平滑肌肥大和嗜酸性食管炎纤维化基因表达。
J Allergy Clin Immunol. 2016 Apr;137(4):1270-1272.e1. doi: 10.1016/j.jaci.2015.09.020. Epub 2015 Nov 2.
2
Esophageal epithelial cells acquire functional characteristics of activated myofibroblasts after undergoing an epithelial to mesenchymal transition.食管上皮细胞在经历上皮-间充质转化后获得活化肌成纤维细胞的功能特性。
Exp Cell Res. 2015 Jan 1;330(1):102-10. doi: 10.1016/j.yexcr.2014.08.026. Epub 2014 Aug 27.
3
T-helper 2 cytokines, transforming growth factor β1, and eosinophil products induce fibrogenesis and alter muscle motility in patients with eosinophilic esophagitis.辅助性 T 细胞 2 细胞因子、转化生长因子-β1 和嗜酸性粒细胞产物可诱导纤维化,并改变嗜酸性粒细胞性食管炎患者的肌肉运动。
Gastroenterology. 2014 May;146(5):1266-77.e1-9. doi: 10.1053/j.gastro.2014.01.051. Epub 2014 Jan 28.
4
High prevalence of eosinophilic esophagitis in patients with inherited connective tissue disorders.遗传性结缔组织疾病患者中嗜酸性食管炎的高发率。
J Allergy Clin Immunol. 2013 Aug;132(2):378-86. doi: 10.1016/j.jaci.2013.02.030. Epub 2013 Apr 19.
5
Eosinophilic esophagitis: epithelial mesenchymal transition contributes to esophageal remodeling and reverses with treatment.嗜酸性粒细胞性食管炎:上皮-间充质转化促进食管重塑,并可随治疗逆转。
J Allergy Clin Immunol. 2012 May;129(5):1387-1396.e7. doi: 10.1016/j.jaci.2012.03.005. Epub 2012 Apr 1.
6
Eosinophilic esophagitis: updated consensus recommendations for children and adults.嗜酸粒细胞性食管炎:儿童和成人的最新共识建议。
J Allergy Clin Immunol. 2011 Jul;128(1):3-20.e6; quiz 21-2. doi: 10.1016/j.jaci.2011.02.040. Epub 2011 Apr 7.
7
Mast cells infiltrate the esophageal smooth muscle in patients with eosinophilic esophagitis, express TGF-β1, and increase esophageal smooth muscle contraction.肥大细胞浸润嗜酸性粒细胞性食管炎患者的食管平滑肌,表达 TGF-β1,并增加食管平滑肌收缩。
J Allergy Clin Immunol. 2010 Dec;126(6):1198-204.e4. doi: 10.1016/j.jaci.2010.08.050. Epub 2010 Nov 3.