Department of Radiation Oncology, University of Nebraska Medical Center, Omaha, Nebraska.
Department of Radiation Oncology, University of Texas M.D. Anderson Cancer Center, Houston, Texas.
Clin Cancer Res. 2016 Oct 1;22(19):4763-4765. doi: 10.1158/1078-0432.CCR-16-1512. Epub 2016 Jul 25.
Siva and colleagues have demonstrated that localized thoracic radiation resulted in DNA damage at out-of-field sites. Although these interesting findings require validation, we discuss the important clinical implications of these data, especially in the era of immune therapies. Clin Cancer Res; 22(19); 4763-5. ©2016 AACRSee related article by Siva et al., p. 4817.
希瓦等人已经证实,局部胸部放射治疗会导致场域外部位的 DNA 损伤。尽管这些有趣的发现需要进一步验证,但我们还是要讨论这些数据的重要临床意义,尤其是在免疫治疗时代。临床癌症研究;22(19);4763-5. ©2016AACR 参见希瓦等人的相关文章,第 4817 页。