Sinha Rajiv, Raut Sumantra
Rajiv Sinha, Paediatric Nephrology, Department of Pediatrics, Institute of Child Health, Kolkata 700017, West Bengal, India.
World J Nephrol. 2016 Jul 6;5(4):328-38. doi: 10.5527/wjn.v5.i4.328.
Nocturnal enuresis often causes considerable distress or functional impairment to patient and their parents necessitating a multidisciplinary approach from paediatrician, paediatric nephrologist, urologists and psychiatrist. Mechanisms of monosymptomatic nocturnal enuresis are mainly nocturnal polyuria, bladder overactivity and failure to awaken from sleep in response to bladder sensations. Goal oriented and etiology wise treatment includes simple behavioral intervention, conditioning alarm regimen and pharmacotherapy with desmopressin, imipramine and anticholinergic drugs. Symptoms often recurs requiring change over or combination of different modes of treatment.
夜间遗尿症常常给患者及其父母带来极大的困扰或功能损害,因此需要儿科医生、儿科肾病学家、泌尿科医生和精神科医生采取多学科方法进行治疗。单纯症状性夜间遗尿症的机制主要是夜间多尿、膀胱过度活动以及未能因膀胱感觉而从睡眠中醒来。以目标为导向且基于病因的治疗包括简单的行为干预、条件警报疗法以及使用去氨加压素、丙咪嗪和抗胆碱能药物进行药物治疗。症状常常复发,需要更换或联合不同的治疗方式。