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2
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3
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Alcohol Res Health. 2010;33(3):229-36.
4
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在合并或未合并丙型肝炎的HIV感染者中,饮酒原因作为一年后酒精使用情况预测因素的研究

Reasons for drinking as predictors of alcohol involvement one year later among HIV-infected individuals with and without hepatitis C.

作者信息

Elliott Jennifer C, Stohl Malka, Aharonovich Efrat, O'Leary Ann, Hasin Deborah S

机构信息

a Department of Psychiatry , Columbia University Medical Center , New York , USA.

b New York State Psychiatric Institute , New York , USA.

出版信息

Ann Med. 2016 Dec;48(8):634-640. doi: 10.1080/07853890.2016.1206668. Epub 2016 Jul 27.

DOI:10.1080/07853890.2016.1206668
PMID:27460482
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5201313/
Abstract

INTRODUCTION

Heavy drinking can be harmful for individuals with HIV, particularly those coinfected with hepatitis C virus (HCV). HIV patients' reasons for drinking predict short-term alcohol involvement, but whether they predict longer-term involvement is unknown. Also, it remains unknown whether these motives are differentially predictive for HIV monoinfected and HIV/HCV coinfected patients.

METHOD

HIV-infected heavy drinkers (n = 254) participated in a randomized trial of brief alcohol interventions, 236 (92.9%) of whom reported on baseline motives and alcohol involvement 12 months later (77.1% male, 94.9% minority, 30.6% with HCV).

RESULTS

Greater endorsement of baseline drinking to cope with negative affect predicted greater alcohol dependence symptoms at 12 months (incident rate ratio [IRR] = 1.80, p < 0.05), while greater endorsement of baseline drinking due to social pressure predicted fewer drinks consumed at 12 months (IRR = 0.67, p < 0.05). Coping and social reasons were both predictive for HIV monoinfected patients, whereas only coping reasons were predictive for HIV/HCV coinfected patients.

DISCUSSION

Drinking for coping and social reasons predict alcohol involvement 12 months later; however, social reasons may only be important for HIV monoinfected patients. Understanding patient reasons for drinking may help predict patient risk up to a year later. KEY MESSAGES Among HIV patients, drinking motives predict alcohol involvement 12 months later. For HIV monoinfected patients, drinking to cope and drinking for social reasons predict 12-month alcohol involvement. For HIV/Hepatitis C coinfected patients, coping (but not social) motives predict 12-month alcohol involvement.

摘要

引言

大量饮酒对感染艾滋病毒的个体有害,尤其是那些同时感染丙型肝炎病毒(HCV)的人。艾滋病毒患者饮酒的原因可预测短期饮酒情况,但能否预测长期饮酒情况尚不清楚。此外,这些动机对单纯感染艾滋病毒和艾滋病毒/丙型肝炎病毒合并感染患者的预测是否存在差异也不清楚。

方法

感染艾滋病毒的酗酒者(n = 254)参与了一项简短酒精干预的随机试验,其中236人(92.9%)报告了基线动机以及12个月后的饮酒情况(77.1%为男性,94.9%为少数族裔,30.6%感染丙型肝炎病毒)。

结果

更多认可为应对负面影响而在基线时饮酒,预测12个月时会出现更多酒精依赖症状(发生率比[IRR] = 1.80,p < 0.05),而更多因社会压力在基线时饮酒,则预测12个月时饮酒量较少(IRR = 0.67,p < 0.05)。应对和社交原因对单纯感染艾滋病毒的患者均有预测作用,而只有应对原因对艾滋病毒/丙型肝炎病毒合并感染的患者有预测作用。

讨论

因应对和社交原因饮酒可预测12个月后的饮酒情况;然而,社交原因可能仅对单纯感染艾滋病毒的患者重要。了解患者饮酒的原因可能有助于预测长达一年后的患者风险。关键信息 在艾滋病毒患者中,饮酒动机可预测12个月后的饮酒情况。对于单纯感染艾滋病毒的患者,为应对和社交原因饮酒可预测12个月后的饮酒情况。对于艾滋病毒/丙型肝炎病毒合并感染的患者,应对(而非社交)动机可预测12个月后的饮酒情况。