台湾一家三级转诊中心葡萄膜炎的发病模式和病因。
Patterns and Etiologies of Uveitis at a Tertiary Referral Center in Taiwan.
机构信息
a Department of Ophthalmology , Kaohsiung Veterans General Hospital , Kaohsiung , Taiwan and.
b School of Medicine , National Yang-Ming University , Taipei , Taiwan.
出版信息
Ocul Immunol Inflamm. 2017;25(sup1):S31-S38. doi: 10.1080/09273948.2016.1189577. Epub 2016 Jul 27.
PURPOSE
To analyze the patterns and etiologies of uveitis at a tertiary referral center in Taiwan.
METHODS
This retrospective chart review of uveitis patients from January 2001 to December 2014 updates a previous study a decade ago (2003).
RESULTS
We identified 450 patients, among whom anterior uveitis was most common, followed by panuveitis, posterior uveitis, and intermediate uveitis. A specific diagnosis was identified in 331 patients. In 73 infectious uveitis cases, herpetic anterior uveitis was the leading cause, followed by endogenous bacterial endophthalmitis and acute retinal necrosis. In 258 non-infectious uveitis cases, HLA-B27-associated uveitis was most commonly seen, followed by Vogt-Koyanagi-Harada disease and Posner-Schlossman syndrome. Compared with our previous study, we found more viral infection and sarcoidosis but fewer cases of Behçet disease, tuberculosis, and toxoplasmosis.
CONCLUSIONS
Our results provide useful information about the patterns and etiologies of uveitis in a selected population in Taiwan.
目的
分析台湾一家三级转诊中心葡萄膜炎的发病模式和病因。
方法
本研究为回顾性图表分析，纳入了 2001 年 1 月至 2014 年 12 月间的葡萄膜炎患者，对 10 年前（2003 年）的一项研究进行了更新。
结果
我们共纳入 450 例患者，其中前葡萄膜炎最常见，其次是全葡萄膜炎、后葡萄膜炎和中间葡萄膜炎。331 例患者明确了具体诊断。在 73 例感染性葡萄膜炎中，单纯疱疹性前葡萄膜炎是最主要的病因，其次是内源性细菌性眼内炎和急性视网膜坏死。在 258 例非感染性葡萄膜炎中，HLA-B27 相关葡萄膜炎最常见，其次是 Vogt-Koyanagi-Harada 病和 Posner-Schlossman 综合征。与我们之前的研究相比，我们发现更多的病毒感染和结节病，但较少的贝切特病、结核病和弓形虫病。
结论
我们的研究结果为台湾特定人群葡萄膜炎的发病模式和病因提供了有用的信息。
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