MR1的发现。
MR1 discovery.
作者信息
Hashimoto Keiichiro
机构信息
Department of Biomedical Polymer Science, Institute for Comprehensive Medical Science, Fujita Health University, Toyoake, Aichi, 470-1192, Japan.
出版信息
Immunogenetics. 2016 Aug;68(8):491-8. doi: 10.1007/s00251-016-0943-9. Epub 2016 Jul 27.
The moment of MR1 discovery is described. The MR1 gene is the first and the last reported human MHC-related gene intentionally isolated from the human genome composed of three billion base pairs. Evolutionary considerations formed the basis of its isolation. Some details surrounding the moment and some retrospective descriptions with various kinds of encounters are also included.
文中描述了MR1发现的时刻。MR1基因是首个也是最后一个被报道的、从由30亿个碱基对组成的人类基因组中有意分离出来的与人类主要组织相容性复合体（MHC）相关的基因。对进化的考量构成了其分离的基础。文中还包含了围绕这一时刻的一些细节以及对各种遭遇的回顾性描述。
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