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贝格曼小骨(永存终末小骨):简要综述及与齿突其他表现的鉴别

Bergmann's ossicle (ossiculum terminale persistens): a brief review and differentiation from other findings of the odontoid process.

作者信息

Johal Jaspreet, Loukas Marios, Fisahn Christian, Oskouian Rod J, Tubbs R Shane

机构信息

Department of Anatomical Sciences, St. George's University, True Blue, St. George's, Grenada.

Seattle Science Foundation, Seattle, WA, USA.

出版信息

Childs Nerv Syst. 2016 Sep;32(9):1603-6. doi: 10.1007/s00381-016-3199-7. Epub 2016 Jul 27.

DOI:10.1007/s00381-016-3199-7
PMID:27465675
Abstract

PURPOSE

The purpose of this paper was to review the literature on Bergmann's ossicle and provide an overview on its development, etiology, and clinical presentation while also differentiating it from similar structural anomalies.

METHODS

A thorough review of the literature available on Bergmann's ossicle was performed.

RESULTS

Bergmann's ossicle, also referred to as ossiculum terminale persistens, was defined as a developmental anomaly of the odontoid process in which an ossification center that gives rise to the tip of the dens fails to fuse properly with the body of the axis.

CONCLUSION

Bergmann's ossicle is most often a benign condition, although it rarely may present with clinical symptoms such as neck pain and neurological signs. It may be associated with Down's syndrome and contribute to atlantoaxial instability.

摘要

目的

本文旨在回顾关于贝格曼小骨的文献,并概述其发育、病因及临床表现,同时将其与类似的结构异常相鉴别。

方法

对现有关于贝格曼小骨的文献进行全面回顾。

结果

贝格曼小骨,也称为永存终末小骨,被定义为齿突的一种发育异常,即形成齿突尖的一个骨化中心未能与枢椎体正常融合。

结论

贝格曼小骨通常为良性情况,尽管它很少会出现颈部疼痛和神经体征等临床症状。它可能与唐氏综合征相关,并导致寰枢椎不稳。

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1
Bergmann's ossicle (ossiculum terminale persistens): a brief review and differentiation from other findings of the odontoid process.贝格曼小骨(永存终末小骨):简要综述及与齿突其他表现的鉴别
Childs Nerv Syst. 2016 Sep;32(9):1603-6. doi: 10.1007/s00381-016-3199-7. Epub 2016 Jul 27.
2
Atlantoaxial instability in a 7-year-old boy associated with traumatic disrupture of the ossiculum terminale (apical odontoid epiphysis).
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"Orthotopic" ossiculum terminale persistens and atlantoaxial instability in a child less than 12 years of age: a case report and review of the literature.
Cases J. 2009 Aug 13;2:8530. doi: 10.4076/1757-1626-2-8530.
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[Ossiculum terminale (Bergmann). Differential diagnosis of an odontoid fracture of the Anderson I type].[终末小骨(伯格曼氏)。安德森I型齿状突骨折的鉴别诊断]
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Atlantoaxial instability and myelopathy due to an ossiculum terminale persistens.持续性终末小骨导致的寰枢椎不稳和脊髓病。
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Atlantoaxial instability and abnormalities of the odontoid in Down's syndrome.唐氏综合征中的寰枢椎不稳定和齿状突异常。
Arch Dis Child. 1988 Dec;63(12):1484-9. doi: 10.1136/adc.63.12.1484.
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Cervical myelopathy involving os odontoideum with retro-odontoid cyst and atlanto-axial instability: A case report.伴有齿突后囊肿及寰枢椎不稳的齿突骨折致颈脊髓病:一例报告
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本文引用的文献

1
The odontoid process: a comprehensive review of its anatomy, embryology, and variations.齿突:对其解剖学、胚胎学及变异的全面综述
Childs Nerv Syst. 2015 Nov;31(11):2025-34. doi: 10.1007/s00381-015-2866-4. Epub 2015 Aug 8.
2
The Dens: Normal Development, Developmental Variants and Anomalies, and Traumatic Injuries.齿突:正常发育、发育变异与异常以及创伤性损伤
J Clin Imaging Sci. 2015 Jun 30;5:38. doi: 10.4103/2156-7514.159565. eCollection 2015.
3
Embryology and bony malformations of the craniovertebral junction.颅颈交界区的胚胎学与骨畸形
Atlantoaxial Stabilization by Posterior C1 and C2 Screw-Rod Fixation for Various Pathologies: Case Series and Comprehensive Review of Literature.
后路C1和C2螺钉-棒固定治疗多种病变的寰枢椎稳定:病例系列及文献综述
J Neurosci Rural Pract. 2021 Apr;12(2):228-235. doi: 10.1055/s-0041-1722838. Epub 2021 Mar 3.
4
Atlantoaxial dislocation due to os odontoideum in patients with Down's syndrome: literature review and case reports.唐氏综合征患者因齿突骨导致的寰枢椎脱位:文献综述与病例报告
Childs Nerv Syst. 2020 Jan;36(1):19-26. doi: 10.1007/s00381-019-04401-y. Epub 2019 Nov 3.
5
Os odontoideum: diagnosis and role of imaging.齿突骨:影像学诊断及作用
Surg Radiol Anat. 2020 Feb;42(2):155-160. doi: 10.1007/s00276-019-02351-3. Epub 2019 Oct 15.
Childs Nerv Syst. 2011 Apr;27(4):523-64. doi: 10.1007/s00381-010-1358-9. Epub 2010 Dec 31.
4
"Orthotopic" ossiculum terminale persistens and atlantoaxial instability in a child less than 12 years of age: a case report and review of the literature.
Cases J. 2009 Aug 13;2:8530. doi: 10.4076/1757-1626-2-8530.
5
Os odontoideum revisited: the case for a multifactorial etiology.再探齿突骨:多因素病因学说
Spine (Phila Pa 1976). 2006 Apr 20;31(9):979-84. doi: 10.1097/01.brs.0000214935.70868.1c.
6
Atlantoaxial instability and myelopathy due to an ossiculum terminale persistens.持续性终末小骨导致的寰枢椎不稳和脊髓病。
Med Sci Monit. 2004 Oct;10(10):CS63-7. Epub 2004 Sep 23.
7
THE OS ODONTOIDEUM. SEPARATE ODONTOID PROCESS.齿突游离小骨。独立齿突
J Bone Joint Surg Am. 1963 Oct;45:1459-71.
8
Atlantoaxial stability in ossiculum terminale. Case report.
J Neurosurg. 2001 Jul;95(1 Suppl):119-21. doi: 10.3171/spi.2001.95.1.0119.
9
Craniovertebral junction: normal anatomy, craniometry, and congenital anomalies.颅颈交界区:正常解剖、颅骨测量及先天性异常
Radiographics. 1994 Mar;14(2):255-77. doi: 10.1148/radiographics.14.2.8190952.
10
Os Odontoideum.齿突骨
J Bone Joint Surg Am. 1980 Apr;62(3):376-83.