Babizhayev M A, Deyev A I, Derevyagin V I
Moscow Helmholtz Research Institute of Eye Diseases 14/19, U.S.S.R.
J Microsc. 1989 May;154(Pt 2):115-27. doi: 10.1111/j.1365-2818.1989.tb00575.x.
A method of classifying cataractous changes in excised human lenses, based on separate and independent photographic documentation, with consequent quantitative evaluation of lens opacification is proposed. The degree of lens clouding was evaluated quantitatively by measuring the optical density index and the area of the zones of clouding with certain optical density parameters (equidensities) by use of an image analyser. This technique produced an image in which contrast represented different zones of lens clouding in the frontal projection, and allowed their contribution to the total lens area to be determined. The precise topography of the opacities was established. The classification data obtained for different clinical types of cataracts can be simplified according to the needs of the scientist in his effort to measure clinically or scientifically significant quantitative associations between laboratory measures and cataractous changes.
本文提出了一种基于独立的摄影记录对切除的人晶状体白内障变化进行分类的方法，并对晶状体混浊进行定量评估。通过使用图像分析仪，测量光学密度指数以及具有特定光学密度参数（等密度）的混浊区域面积，对晶状体混浊程度进行定量评估。该技术生成的图像中，对比度代表了晶状体正面投影中不同的混浊区域，并能够确定它们在晶状体总面积中所占的比例。确定了混浊的精确地形图。针对不同临床类型白内障获得的分类数据，可根据科学家在测量实验室指标与白内障变化之间具有临床或科学意义的定量关联时的需求进行简化。
