Chylack L T
Ciba Found Symp. 1984;106:3-24. doi: 10.1002/9780470720875.ch2.
The American Cooperative Cataract Research Group (CCRG) has adopted a system of classifying cataractous changes in excised human cataracts that is based on separate and independent photographic documentation of opacification and nuclear colour. The classification data can be simplified according to the needs of the scientist in his or her effort to measure clinically or scientifically significant associations between laboratory measures and cataractous change. The association between nuclear colour and the extent of cortical opacification and the intensity of nuclear opacification has been studied and found to be insignificant. These results justify the recommendation that nuclear colour be abandoned as the single index of severity of any type of senile cataractous change. The adaptability of this system to in vivo use in epidemiological and other studies of the natural history of cataractous change is discussed. Its limitations are outlined. The system may offer a basis for international cooperation in cataract classification.
美国白内障合作研究小组（CCRG）采用了一种对切除的人类白内障中的白内障变化进行分类的系统，该系统基于对混浊和核颜色的单独且独立的摄影记录。根据科学家在测量实验室指标与白内障变化之间临床或科学上显著关联的努力中的需求，可以简化分类数据。已经研究了核颜色与皮质混浊程度以及核混浊强度之间的关联，发现其不显著。这些结果证明了建议放弃将核颜色作为任何类型老年性白内障变化严重程度的单一指标是合理的。讨论了该系统在白内障变化自然史的流行病学及其他研究中用于体内研究的适应性。概述了其局限性。该系统可能为白内障分类的国际合作提供基础。
