Zhou S-F, Yin J-B, Yang H, Zhong J, An P
Department of Ultrasound Imaging, Xiangyang Hospital Affiliated to Hubei University of Medicine, Xiangyang, Hubei Province, China.
Eur Rev Med Pharmacol Sci. 2016 Jul;20(15):3206-10.
To explore the imaging characteristics and clinical application value of gastric filling ultrasound combined with an intravenous contrast agent (double contrast ultrasonography, DCUS) in the diagnosis of advanced gastric carcinoma.
Totally 48 patients with advanced gastric carcinoma were confirmed by endoscopic biopsy and then administrated with DCUS and enhanced magnetic resonance examination before treatment. Retrospective analysis was conducted based on the characteristics of their ultrasonic images, and the results of diagnosis were compared and analyzed between the DCUS technology and the enhanced magnetic resonance examination.
The DCUS technology showed rapid positive development in the arterial phase and rapid negative development in the portal phase at all foci of advanced gastric carcinomas. The initiation time in the arterial phase was (19.35±4.82) s, the peak value was (31.41±4.23) dB, and the expurgation time was (41.71±7.03) s. The accuracy rates of the DCUS diagnosis and the enhanced magnetic resonance diagnosis of advanced gastric cancer were 87.5% and 66.7% respectively, with statistical differences (p<0.05).
DCUS had specific fast-in and fast-out characteristics and high accuracy in diagnosing the advanced gastric cancer and so could be used as an effective means to the diagnosis of the disease in clinic.
探讨胃充盈超声联合静脉造影剂（双对比超声检查，DCUS）在进展期胃癌诊断中的影像学特征及临床应用价值。
48例进展期胃癌患者经内镜活检确诊，治疗前接受DCUS及增强磁共振检查。基于超声图像特征进行回顾性分析，比较并分析DCUS技术与增强磁共振检查的诊断结果。
DCUS技术在进展期胃癌各病灶动脉期呈快速阳性显影，门脉期呈快速阴性显影。动脉期起始时间为（19.35±4.82）秒，峰值为（31.41±4.23）分贝，消退时间为（41.71±7.03）秒。DCUS诊断进展期胃癌的准确率为87.5%，增强磁共振诊断的准确率为66.7%，差异有统计学意义（p<0.05）。
DCUS在诊断进展期胃癌方面具有特异性的快进快出特征及较高准确性，可作为临床诊断该疾病的有效手段。
