Williams Michelle D
Department of Pathology, Head and Neck Section, MD Anderson Cancer Center, The University of Texas, 1515 Holcombe Blvd, Unit 085, Houston, TX, 77030, USA.
Curr Oncol Rep. 2016 Sep;18(9):54. doi: 10.1007/s11912-016-0540-y.
Margin assessment remains a critical component of oncologic care for head and neck cancer patients. As an integrated team, both surgeons and pathologists work together to assess margins in these complex patients. Differences in method of margin sampling can impact obtainable information and effect outcomes. Additionally, what distance is an "adequate or clear" margin for patient care continues to be debated. Ultimately, future studies and potentially secondary modalities to augment pathologic assessment of margin assessment (i.e., in situ imaging or molecular assessment) may enhance local control in head and neck cancer patients.
切缘评估仍然是头颈癌患者肿瘤治疗的关键组成部分。作为一个综合团队，外科医生和病理学家共同努力评估这些复杂患者的切缘情况。切缘取样方法的差异会影响可获得的信息并影响治疗结果。此外，对于患者治疗而言，多大的切缘距离算是“足够或清晰”仍存在争议。最终，未来的研究以及可能用于辅助切缘评估病理检查的二级检查手段（即原位成像或分子评估）可能会提高头颈癌患者的局部控制率。
