Vanithakumari G, Manonayagi S, Padma S, Malini T
Department of Endocrinology, Postgraduate Institute of Basic Medical Sciences, Madras, India.
J Ethnopharmacol. 1989 Apr;25(2):173-80. doi: 10.1016/0378-8741(89)90019-6.
An ethanolic extract of Bambusa arundinacea tender shoots (BASE) caused a reduction in fertility of male rats. After administration of 300 mg/kg per day of BASE for 7 days, the fertility index decreased to 15% for control rats and to 23% after a 7-day recovery period, respectively. The number of cohabited females being successfully inseminated was reduced especially after 4 days of treatment. Complete recovery of mating behaviour was evident 8 days after BASE withdrawal. The number of spermatozoa in the caput and cauda epididymis were decreased concomitant with a decrease in the motility of spermatozoa collected from the cauda epididymis. The weights of testes, epididymides, vas deferens and prostate were also significantly decreased. The serum profile of protein and oxaloacetic/pyruvic transaminase activity show the extract to be relatively non-toxic.
簕竹嫩枝乙醇提取物（BASE）可导致雄性大鼠生育力下降。每天给予300 mg/kg的BASE，持续7天，对照大鼠的生育指数分别降至15%，经过7天的恢复期后降至23%。成功受孕的同居雌性数量减少，尤其是在治疗4天后。停用BASE 8天后，交配行为明显完全恢复。附睾头和附睾尾中的精子数量减少，同时从附睾尾采集的精子活力也下降。睾丸、附睾、输精管和前列腺的重量也显著降低。蛋白质和草酰乙酸/丙酮酸转氨酶活性的血清谱显示该提取物相对无毒。
