Shukla S, Mathur R, Prakash A O
Laboratory of Reproductive Biology, School of Studies in Zoology, Jiwaji University, Gwalior, India.
J Ethnopharmacol. 1989 May;25(3):249-61. doi: 10.1016/0378-8741(89)90031-7.
The effect of an aqueous extract of Moringa oleifera roots was studied histologically on the genital tract of ovariectomized rats in the presence and absence of estradiol dipropionate and progesterone. Administration of the extract itself stimulated the uterine histoarchitecture as revealed by increases in the height of luminal epithelium, well developed glands, loose stroma and rich vascularity. The cervix showed metaplastic changes in the epithelium with marked keratinization. In the vagina, cornification was very prominent, rugae increased and stroma was loose. Conjoint administration of the extract with estradiol showed a synergistic action, and an inhibition was observed when administered conjointly with progesterone.
在有和没有二丙酸雌二醇及孕酮的情况下，对去卵巢大鼠的生殖道进行组织学研究，以探讨辣木根水提取物的作用。提取物本身的给药刺激了子宫组织结构，表现为管腔上皮高度增加、腺体发育良好、间质疏松和血管丰富。子宫颈上皮出现化生变化并伴有明显的角化。在阴道中，角化非常明显，皱襞增加且间质疏松。提取物与雌二醇联合给药显示出协同作用，而与孕酮联合给药时则观察到抑制作用。
