Aragoncillo C, Rodríguez-Loperena M A, Salcedo G, Carbonero P, García-Olmedo F
Proc Natl Acad Sci U S A. 1978 Mar;75(3):1446-50. doi: 10.1073/pnas.75.3.1446.
Gene-dosage responses for a group of six wheat endosperm proteins have been investigated by using compensated nulli-tetrasomic lines of cv. Chinese Spring. Practically linear dosage responses have been observed for all the proteins. However, for two of the proteins (and probably for a third one), the net output of protein, at each dosage of its structural gene, was 30-80% higher when the chromosome carrying an active homoeogene was absent. The possible significance of this effect in connection with the loss of gene redundancy undergone by polyploids is discussed.
利用中国春品种的补偿缺体-四体品系，对一组六种小麦胚乳蛋白的基因剂量反应进行了研究。实际上，所有蛋白质都观察到了近似线性的剂量反应。然而，对于其中两种蛋白质（可能还有第三种），当携带活性同源基因的染色体缺失时，其结构基因在每个剂量下的蛋白质净产量要高出30%-80%。文中讨论了这种效应与多倍体所经历的基因冗余丧失相关的可能意义。
