Guo Runqi, Yu Wei, Meng Yisen, Zhang Kai, Xu Ben, Xiao Yunxiang, Wu Shiliang, Pan Bainian
Department of Urology, Peking University First Hospital and Institute of Urology, National Research Center for Genitourinary Oncology, Beijing, China.
Department of Urology, Peking University First Hospital and Institute of Urology, National Research Center for Genitourinary Oncology, Beijing, China.
Urology. 2016 Dec;98:120-125. doi: 10.1016/j.urology.2016.07.025. Epub 2016 Jul 26.
To re-assess the Charlson Comorbidity Index (CCI) and the American Society of Anesthesiologists Physical Status Classification System (ASA grade) as predictive factors of complications after transurethral resection of prostate.
This study retrospectively included and analyzed consecutive patients undergoing transurethral resection of the prostate at Peking University First Hospital between 1992 and 2013. A multivariate analysis was conducted to evaluate the connection of the ASA and CCI grades with the incidence of complications.
This paper studied 2326 cases in total. The CCI and ASA grades were significantly correlated, with a Spearman ρ of 0.245 (P <.001). No considerable differences among the patient cohorts with different CCI or ASA grades were observed in terms of day of catheter removal, surgical time, and prostate size. In addition, no considerable differences were observed in the different modified Clavien classification system scores of complications among patient cohorts with different grades of CCI.
The majority of complications (86.9%) were of grades I, II, and III, whereas grade IV was less frequent (12.1%), and, after transurethral resection of the prostate, grade V was rare (1%). Males with an ASA grade ≥3 and higher CCI scores were more likely to demonstrate a higher incidence of morbidity than males with a lower grade. However, ASA grades and CCI scores were not independent predictors of complications because of the experience of the surgeon and progress in perioperative management and operative techniques. Therefore, for patients with more comorbidities and higher CCI scores or ASA grades, active surgical intervention is still suggested.
重新评估查尔森合并症指数(CCI)和美国麻醉医师协会身体状况分类系统(ASA分级)作为经尿道前列腺电切术后并发症的预测因素。
本研究回顾性纳入并分析了1992年至2013年期间在北京大学第一医院接受经尿道前列腺电切术的连续患者。进行多因素分析以评估ASA分级和CCI分级与并发症发生率之间的关联。
本文共研究了2326例病例。CCI分级与ASA分级显著相关,Spearman ρ为0.245(P <.001)。在不同CCI或ASA分级的患者队列中,导尿管拔除日、手术时间和前列腺大小方面未观察到显著差异。此外,不同CCI分级的患者队列在并发症的不同改良Clavien分类系统评分方面也未观察到显著差异。
大多数并发症(86.9%)为I、II和III级,而IV级较少见(12.1%),经尿道前列腺电切术后V级罕见(1%)。ASA分级≥3且CCI评分较高的男性比分级较低的男性更有可能表现出更高的发病率。然而,由于外科医生的经验以及围手术期管理和手术技术的进步,ASA分级和CCI评分并非并发症的独立预测因素。因此,对于合并症更多、CCI评分或ASA分级更高的患者,仍建议积极进行手术干预。