Gaskins Audrey J, Williams Paige L, Keller Myra G, Souter Irene, Hauser Russ, Chavarro Jorge E
Department of Nutrition, Harvard TH Chan School of Public Health, 655 Huntington Avenue, Boston, MA 02115, USA; Department of Epidemiology, Harvard TH Chan School of Public Health, 655 Huntington Avenue, Boston, MA 02115, USA.
Department of Epidemiology, Harvard TH Chan School of Public Health, 655 Huntington Avenue, Boston, MA 02115, USA; Department of Biostatistics, Harvard TH Chan School of Public Health, 655 Huntington Avenue, Boston, MA 02115, USA.
Reprod Biomed Online. 2016 Oct;33(4):513-521. doi: 10.1016/j.rbmo.2016.07.002. Epub 2016 Jul 20.
Physical activity could benefit reproductive function through its ability to regulate energy balance and improve insulin sensitivity, but its association with IVF outcomes remains unclear. The aim of this study was to evaluate whether pre-treatment physical and sedentary activity is associated with outcomes of IVF. The Environment and Reproductive Health Study is an ongoing prospective cohort study that enrols subfertile couples at Massachusetts General Hospital Fertility Center. Time spent in physical and sedentary activities in the year before IVF treatment is self-reported using a validated questionnaire. This analysis included 273 women who underwent 427 IVF cycles. Women engaged in a median of 2.8 h per week of moderate-to-vigorous activities. Time spent in moderate-to-vigorous physical activities and total metabolic equivalent task hours before IVF were not associated with probability of implantation, clinical pregnancy or live birth. Of the specific physical activities, only greater time spent in aerobics, rowing, and on the ski or stair machine was associated with higher probability of live birth. Time spent in total and specific sedentary activities were not associated with clinical outcomes of IVF. Physical activity is unlikely to have a deleterious effect on IVF success and certain forms of vigorous activity may be beneficial.
体育活动可通过调节能量平衡和改善胰岛素敏感性来有益于生殖功能，但其与体外受精（IVF）结局的关联仍不明确。本研究的目的是评估IVF治疗前的体育活动和久坐行为是否与IVF结局相关。环境与生殖健康研究是一项正在进行的前瞻性队列研究，纳入了马萨诸塞州总医院生育中心的亚生育夫妇。使用经过验证的问卷自我报告IVF治疗前一年在体育活动和久坐行为上花费的时间。该分析纳入了273名接受427个IVF周期的女性。女性每周进行中度至剧烈活动的时间中位数为2.8小时。IVF前进行中度至剧烈体育活动的时间和总代谢当量任务小时数与着床概率、临床妊娠或活产无关。在特定的体育活动中，只有花更多时间进行有氧运动、划船以及在滑雪机或楼梯机上运动与更高的活产概率相关。在总的和特定的久坐行为上花费的时间与IVF的临床结局无关。体育活动不太可能对IVF成功产生有害影响，某些形式的剧烈活动可能有益。
