Kovarski K, Thillay A, Houy-Durand E, Roux S, Bidet-Caulet A, Bonnet-Brilhault F, Batty M
Inserm, UMR U930 Imagerie et Cerveau, CHRU de Tours, Centre Universitaire de PédoPsychiatrie, Université François-Rabelais de Tours, 2 Blv Tonnellé, 37044, Tours, France.
Inserm, U1028, CNRS UMRS5292, Centre de Recherche en Neurosciences de Lyon, Bron, France.
J Autism Dev Disord. 2016 Oct;46(10):3377-86. doi: 10.1007/s10803-016-2880-8.
Autism spectrum disorder (ASD) is characterized by atypical visual perception both in the social and nonsocial domain. In order to measure a reliable visual response, visual evoked potentials were recorded during a passive pattern-reversal stimulation in adolescents and adults with and without ASD. While the present results show the same age-related changes in both autistic and non-autistic groups, they reveal a smaller P100 amplitude in the ASD group compared to controls. These results confirm that early visual responses are affected in ASD even with a simple, non social and passive stimulation and suggest that they should be considered in order to better understand higher-level processes.
自闭症谱系障碍（ASD）的特征是在社交和非社交领域都存在非典型的视觉感知。为了测量可靠的视觉反应，在有和没有ASD的青少年和成年人进行被动模式反转刺激期间记录了视觉诱发电位。虽然目前的结果显示自闭症组和非自闭症组都有相同的年龄相关变化，但与对照组相比，ASD组的P100波幅较小。这些结果证实，即使是简单、非社交和被动的刺激，ASD患者的早期视觉反应也会受到影响，并表明为了更好地理解高级过程，应该考虑这些反应。
