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减肥补充剂中发现的禁用和不建议使用的成分。

Banned and discouraged-use ingredients found in weight loss supplements.

作者信息

Eichner Sara, Maguire Michelle, Shea Leticia A, Fete Matthew G

出版信息

J Am Pharm Assoc (2003). 2016 Sep-Oct;56(5):538-43. doi: 10.1016/j.japh.2016.03.013. Epub 2016 Jul 27.

DOI:10.1016/j.japh.2016.03.013
PMID:27475836
Abstract

OBJECTIVES

To identify banned and discouraged-use ingredients, such as ephedra, 1,3-dimethylamylamine, and beta-methyl-phenylethylamine, in readily available weight loss dietary supplements within a 10-mile radius of Regis University.

METHODS

A list of banned and discouraged-use ingredients was compiled with the use of the Food and Drug Administration (FDA) dietary supplement website which provides information on supplement ingredients that are no longer legal or are advised against owing to adverse event reporting. Investigators visited all retail outlet stores within a 10-mile radius of Regis University in Denver, Colorado. Retail chains were not duplicated and only one of each chain was evaluated.

RESULTS

A total of 51 weight loss supplement products from retail stores were found with banned or discouraged-use substances listed on their labels. At least one banned ingredient was found to be listed on the product labels in 17 of the 51 studied supplements (33%). At least one discouraged-use ingredient was found in 46 of the 51 products (90%). Retail outlet stores dedicated to supplements and sports nutrition alone were found to have the greatest number of weight loss supplements that included banned and discouraged-use ingredients.

CONCLUSION

The FDA has taken action to remove some weight loss supplements from the market that contain banned ingredients. Unfortunately, based on the findings of this study, it is evident that products containing these ingredients remain on the market today.

摘要

目的

在里吉斯大学半径10英里范围内容易获取的减肥膳食补充剂中,识别被禁止和不鼓励使用的成分,如麻黄、1,3 - 二甲基戊胺和β - 甲基苯乙胺。

方法

利用美国食品药品监督管理局(FDA)膳食补充剂网站编制了一份被禁止和不鼓励使用成分的清单,该网站提供了关于因不良事件报告而不再合法或不建议使用的补充剂成分的信息。研究人员走访了科罗拉多州丹佛市里吉斯大学半径10英里范围内的所有零售店。零售连锁店不重复走访,每个连锁店仅评估一家。

结果

在零售店发现的51种减肥补充剂产品中,其标签上列出了被禁止或不鼓励使用的物质。在所研究的51种补充剂中,有17种(33%)的产品标签上至少列出了一种被禁止的成分。在51种产品中有46种(90%)发现了至少一种不鼓励使用的成分。仅专门经营补充剂和运动营养产品的零售店被发现含有被禁止和不鼓励使用成分的减肥补充剂数量最多。

结论

FDA已采取行动将一些含有被禁止成分的减肥补充剂从市场上移除。不幸的是,根据本研究的结果,显然如今含有这些成分的产品仍在市场上。

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