日本育龄妇女的生育次数、孕前体重指数与低体重儿的关系
Combination of parity and pre-pregnancy BMI and low birth weight infants among Japanese women of reproductive age.
作者信息
Suzuki Kounosuke, Nomura Kyoko, Takenoshita Shinichi, Ando Kazumichi, Kido Michiko
机构信息
Japanese Red Cross Medical Center, Tokyo, Japan.
出版信息
Ind Health. 2016 Dec 7;54(6):515-520. doi: 10.2486/indhealth.2016-0088. Epub 2016 Jul 29.
This study aimed to examine the effects of parity and pre-pregnancy body mass index (BMI) on low birth weight (LBW) infants among Japanese women. Participants included 1,518 mothers (mean age 34.0 years) of singleton full-term infants in 2011. The incidence of LBW infants was 7.5% in primiparous women with BMI<18.5 (Group A; n=239), 4.0% in multiparous women with BMI<18.5 (Group B; n=124), 6.0% in primiparous women with 18.5≤BMI<25 (Group C; n=715), and 1.8% in multiparous women with 18.5≤BMI<25 (Group D; n=440). A multivariable logistic regression model revealed that mothers in Group A were more likely to deliver a LBW infant [odds ratio (OR) 6.41, 95% confidence interval (CI), 2.65-15.49] than were mothers in Group D. Being both underweight (OR 1.8, 95% CI: 1.05-3.11) and primiparous (OR 3.41, 95% CI: 1.82-6.44) were independently associated with LBW infants. This study demonstrated that the characteristics of primiparous and underweight in mothers are additively associated with LBW infants.
本研究旨在探讨生育次数和孕前体重指数（BMI）对日本女性低出生体重（LBW）婴儿的影响。研究对象包括2011年1518名单胎足月儿的母亲（平均年龄34.0岁）。BMI<18.5的初产妇中低出生体重儿的发生率为7.5%（A组；n=239），BMI<18.5的经产妇中为4.0%（B组；n=124），18.5≤BMI<25的初产妇中为6.0%（C组；n=715），18.5≤BMI<25的经产妇中为1.8%（D组；n=440）。多变量逻辑回归模型显示，A组母亲比D组母亲更有可能分娩低出生体重儿[比值比（OR）6.41，95%置信区间（CI），2.65 - 15.49]。体重过轻（OR 1.8，95% CI：1.05 - 3.11）和初产（OR 3.41，95% CI：1.82 - 6.44）均与低出生体重儿独立相关。本研究表明，母亲的初产和体重过轻特征与低出生体重儿呈累加关联。
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