Otani Taisuke, Isohata Noriyuki, Kumamoto Kensuke, Endo Shungo, Utano Kenichi, Nemoto Daiki, Aizawa Masato, Lefor Alan K, Togashi Kazutomo
Department of Coloproctology, Aizu Medical Center, Fukushima Medical University.
Fukushima J Med Sci. 2016 Dec 16;62(2):74-82. doi: 10.5387/fms.2016-4. Epub 2016 Jul 30.
During the 1990s, laparoscopic resection was established as a treatment for gastrointestinal malignant tumors. A number of randomized controlled trials comparing laparoscopic-assisted colorectal surgery with conventional open colorectal surgery for colon cancer have been conducted. These trials have shown short-term benefits, and the vast majority demonstrated no significant difference in long-term outcomes. Laparoscopic-assisted colorectal surgery is widely performed for the treatment of colon cancer, whereas laparoscopic-assisted colorectal surgery for rectal cancer is less commonly performed. In recent years, there have been an increasing number of reports of laparoscopic-assisted colorectal surgery for rectal cancer, where improving short-term outcomes was shown, but no definitive effect on long-term survival has been shown to date. Randomized controlled trials focusing on long-term survival are currently ongoing.
在20世纪90年代，腹腔镜切除术成为治疗胃肠道恶性肿瘤的一种方法。已经开展了多项将腹腔镜辅助结直肠癌手术与传统开放性结直肠癌手术用于结肠癌治疗的随机对照试验。这些试验显示了短期获益，并且绝大多数试验表明长期结局无显著差异。腹腔镜辅助结直肠癌手术被广泛用于结肠癌的治疗，而腹腔镜辅助直肠癌手术的开展则较少。近年来，腹腔镜辅助直肠癌手术的报道越来越多，其显示出短期结局有所改善，但迄今为止尚未显示出对长期生存有确切影响。目前正在进行关注长期生存的随机对照试验。
