Fu Zhentao, Lu Zilong, Li Yingmei, Zhang Jiyu, Zhang Gaohui, Chen Xianxian, Chu Jie, Ren Jie, Liu Haiyan, Guo Xiaolei
Shandong Center for Disease Control and Prevention, Jinan 250014, China.
the Second People's Hospital of Jinan, Jinan 250001, China.
Chin J Cancer Res. 2016 Jun;28(3):263-74. doi: 10.21147/j.issn.1000-9604.2016.03.01.
Population-based cancer registration data in 2012 from all available cancer registries in Shandong province were collected by Shandong Center for Disease Control and Prevention (SDCDC). SDCDC estimated the numbers of new cancer cases and cancer deaths in Shandong province with compiled cancer incidence and mortality rates.
In 2015, there were 21 cancer registries submitted data of cancer incidence and deaths occurred in 2012. All the data were checked and evaluated based on the National Central Cancer Registry (NCCR) criteria of data quality. Qualified data from 15 registries were used for cancer statistics analysis as provincial estimation. The pooled data were stratified by area (urban/rural), gender, age group (0, 1.4, 5.9, 10.14, …, 85+ years) and cancer type. New cancer cases and deaths were estimated using age-specific rates and corresponding provincial population in 2012. The Chinese census data in 2000 and Segi's population were applied for age-standardized rates. All the rates were expressed per 100,000 person-year.
Qualified 15 cancer registries (4 urban and 11 rural registries) covered 17,189,988 populations (7,486,039 in urban and 9,703,949 in rural areas). The percentage of cases morphologically verified (MV%) and death certificate-only cases (DCO%) were 66.12% and 2.93%, respectively, and the mortality to incidence rate ratio (M/I) was 0.60. A total of 253,060 new cancer cases and 157,750 cancer deaths were estimated in Shandong province in 2012. The incidence rate was 263.86/100,000 (303.29/100,000 in males, 223.23/100,000 in females), the age-standardized incidence rates by Chinese standard population (ASIRC) and by world standard population (ASIRW) were 192.42/100,000 and 189.50/100,000 with the cumulative incidence rate (0.74 years old) of 22.07%. The cancer incidence, ASIRC and ASIRW in urban areas were 267.64/100,000, 195.27/100,000 and 192.02/100,000 compared to 262.32/100,000, 191.26/100,000 and 188.48/100,000 in rural areas, respectively. The cancer mortality was 164.47/100,000 (207.42/100,000 in males, 120.23/100,000 in females), the age-standardized incidence rates by Chinese standard population (ASMRC) and by world standard population (ASMRW) were 117.54/100,000 and 116.90/100,000, and the cumulative mortality rate (0.74 years old) was 13.53%. The cancer mortality, ASMRC and ASMRW were 141.59/100,000, 101.17/100,000 and 100.33/100,000 in urban areas, and 173.79/100,000, 124.20/100,000 and 123.64/100,000 in rural areas, respectively. Cancers of the lung, stomach, liver, esophagus, colorectum, female breast, brain, leukemia, bladder and pancreas were the most common cancers, accounting for about 82.12% of all cancer new cases. Lung cancer, stomach cancer, liver cancer, esophageal cancer, colorectal cancer, female breast cancer, pancreatic cancer, brain tumor, leukemia and lymphoma were the leading causes of cancer death, accounting for about 89.01% of all cancer deaths. The cancer spectrum showed difference between urban and rural, males and females both in incidence and mortality rates.
Cancer surveillance information in Shandong province is making great progress with the increasing number of cancer registries, population coverage and the improving data quality. Cancer registration plays a fundamental role in cancer control by providing basic information on population-based cancer incidence, mortality, survival and time trend. The disease burden of cancer is serious in Shandong province, and so cancer prevention and control in Shandong province should be enhanced including health education, health promotion, cancer screening and cancer care services.
山东省疾病预防控制中心（SDCDC）收集了2012年山东省所有可用癌症登记处基于人群的癌症登记数据。SDCDC利用编制的癌症发病率和死亡率估算了山东省新癌症病例数和癌症死亡数。
2015年，有21个癌症登记处提交了2012年发生的癌症发病率和死亡数据。所有数据均根据国家癌症中心（NCCR）的数据质量标准进行检查和评估。来自15个登记处的合格数据用于癌症统计分析作为省级估算。汇总数据按地区（城市/农村）、性别、年龄组（0、1 - 4、5 - 9、10 - 14、…、85岁以上）和癌症类型进行分层。使用特定年龄发病率和2012年相应省级人口估算新癌症病例和死亡数。应用2000年中国人口普查数据和Segi人口数据计算年龄标准化率。所有率均以每10万人年表示。
合格的15个癌症登记处（4个城市登记处和11个农村登记处）覆盖了17,189,988人口（城市7,486,039人，农村9,703,949人）。形态学确诊病例百分比（MV%）和仅死亡证明病例百分比（DCO%）分别为66.12%和2.93%，死亡率与发病率之比（M/I）为0.60。2012年山东省估计共有253,060例新癌症病例和157,750例癌症死亡。发病率为263.86/10万（男性为303.29/10万，女性为223.23/10万），中国标准人群年龄标准化发病率（ASIRC）和世界标准人群年龄标准化发病率（ASIRW）分别为192.42/10万和189.50/10万，累积发病率（0 - 74岁）为22.07%。城市地区的癌症发病率、ASIRC和ASIRW分别为267.64/10万、195.27/10万和192.02/10万，农村地区分别为262.32/10万、191.26/10万和188.48/10万。癌症死亡率为164.47/10万（男性为207.42/10万，女性为120.23/10万），中国标准人群年龄标准化发病率（ASMRC）和世界标准人群年龄标准化发病率（ASMRW）分别为117.54/10万和116.90/10万，累积死亡率（0 - 74岁）为13.53%。城市地区的癌症死亡率、ASMRC和ASMRW分别为141.59/10万、101.17/10万和100.33/10万，农村地区分别为173.79/10万、124.20/10万和123.64/10万。肺癌、胃癌、肝癌、食管癌、结直肠癌、女性乳腺癌、脑癌、白血病、膀胱癌和胰腺癌是最常见的癌症，约占所有癌症新病例的82.12%。肺癌、胃癌、肝癌、食管癌、结直肠癌、女性乳腺癌、胰腺癌、脑肿瘤、白血病和淋巴瘤是癌症死亡的主要原因，约占所有癌症死亡的89.01%。癌症谱在城市和农村、男性和女性的发病率和死亡率方面均显示出差异。
随着癌症登记处数量、人口覆盖范围的增加以及数据质量的提高，山东省的癌症监测信息取得了很大进展。癌症登记通过提供基于人群的癌症发病率、死亡率、生存率和时间趋势的基本信息，在癌症控制中发挥着重要作用。山东省的癌症疾病负担严重，因此应加强山东省的癌症预防和控制，包括健康教育、健康促进、癌症筛查和癌症护理服务。
