1型糖尿病成年患者的乳糜泻筛查：误区、事实与争议
Screening for coeliac disease in adult patients with type 1 diabetes mellitus: myths, facts and controversy.
作者信息
Bakker Sjoerd F, Tushuizen Maarten E, von Blomberg Boudewina M E, Bontkes Hetty J, Mulder Chris J, Simsek Suat
机构信息
Department of Gastroenterology and Hepatology, VU University Medical Centre, De Boelelaan 1117, 1081 HV Amsterdam, The Netherlands.
Department of Pathology, Unit Medical Immunology, VU University Medical Centre, Amsterdam, The Netherlands.
出版信息
Diabetol Metab Syndr. 2016 Jul 29;8:51. doi: 10.1186/s13098-016-0166-0. eCollection 2016.
This review aims at summarizing the present knowledge on the clinical consequences of concomitant coeliac disease (CD) in adult patients with type 1 diabetes mellitus (T1DM). The cause of the increased prevalence of CD in T1DM patients is a combination of genetic and environmental factors. Current screening guidelines for CD in adult T1DM patients are not uniform. Based on the current evidence of effects of CD on bone mineral density, diabetic complications, quality of life, morbidity and mortality in patients with T1DM, we advise periodic screening for CD in adult T1DM patients to prevent delay in CD diagnosis and subsequent CD and/or T1DM related complications.
本综述旨在总结目前关于成年1型糖尿病（T1DM）患者合并乳糜泻（CD）的临床后果的知识。T1DM患者中CD患病率增加的原因是遗传和环境因素的综合作用。目前针对成年T1DM患者的CD筛查指南并不统一。基于目前CD对T1DM患者骨矿物质密度、糖尿病并发症、生活质量、发病率和死亡率影响的证据，我们建议对成年T1DM患者进行定期CD筛查，以防止CD诊断延误及随后出现与CD和/或T1DM相关的并发症。
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