Mamalis N, Medlock R D, Holds J B, Anderson R L, Crandall A S
Department of Ophthalmology, University of Utah School of Medicine, Salt Lake City.
Ophthalmic Surg. 1989 Jun;20(6):410-4.
We describe a case of a Merkel cell tumor of the eyelid that manifested as a recurrent chalazion. This tumor had the classic characteristics of a Merkel cell neoplasm by light microscopy. Electron microscopy showed dense-core neurosecretory granules and perinuclear microfilaments consistent with the diagnosis. Because a Merkel cell tumor may manifest as a chalazion, pathologic evaluation of all atypical chalazia is essential. Merkel cell tumors are malignant, and they must be treated aggressively to minimize recurrence or metastasis.
我们描述了一例表现为复发性睑板腺囊肿的眼睑默克尔细胞肿瘤。通过光学显微镜检查，该肿瘤具有默克尔细胞瘤的典型特征。电子显微镜显示有致密核心神经分泌颗粒和核周微丝，与诊断相符。由于默克尔细胞肿瘤可能表现为睑板腺囊肿，因此对所有非典型睑板腺囊肿进行病理评估至关重要。默克尔细胞肿瘤是恶性的，必须积极治疗以尽量减少复发或转移。
