Merkel cell carcinoma of the eyelid. A clinicopathological case report.

Merkel cell carcinoma, a neuroendocrine tumor, is a highly invasive cutaneous neoplasm, which rarely affects the eyelids. This tumor must be treated aggressively to minimize the changes of local recurrence and regional or distant metastasis. In this paper, we describe a 78-year-old woman who had two recurrences of this neoplasm after consecutive local excisions. We describe the histopathological findings and emphasize the differential diagnosis with other neoplasms, as the therapeutic approach is different.