Patel J, Apple D J, Hansen S O, Solomon K D, Tetz M R, Gwin T D, O'Morchoe D J, Daun M E
Department of Ophthalmology, Medical University of South Carolina, Charleston 29401.
Ophthalmology. 1989 May;96(5):598-602. doi: 10.1016/s0161-6420(89)32843-0.
In a clinical study, 61 patients underwent phacoemulsification with subsequent intraocular lens (IOL) implantation. An intercapsular capsulotomy with phacoemulsification was performed on 23 patients and a can opener capsulotomy with phacoemulsification on 38 patients. Wide-field specular microscopy was performed preoperatively and postoperatively on all of the eyes in the study. The cell counts were not divulged to the surgeon before or at the time of surgery. Average endothelial cell loss for the intercapsular technique was 3.9%; with the can opener technique, the average cell loss was 10.1%. This difference was statistically significant (P less than 0.01). Positive correlations between endothelial cell loss relating to ultrasound time and/or the hardness of the cataract existed for the can opener group only (P less than 0.01). These results demonstrate that a protective effect is provided by the presence of the anterior lens capsule during lens substance removal.
在一项临床研究中，61例患者接受了白内障超声乳化吸除术及随后的人工晶状体（IOL）植入术。其中23例患者进行了囊内截囊联合超声乳化术，38例患者进行了开罐式截囊联合超声乳化术。对研究中的所有术眼在术前和术后均进行了广角镜面显微镜检查。细胞计数结果在手术前或手术时均未告知手术医生。囊内技术的平均内皮细胞损失率为3.9%；开罐式技术的平均细胞损失率为10.1%。这一差异具有统计学意义（P＜0.01）。仅在开罐式技术组中，内皮细胞损失与超声时间和/或白内障硬度之间存在正相关（P＜0.01）。这些结果表明，在晶状体物质摘除过程中，前囊膜的存在具有保护作用。
