Sasaki A, Inoue T, Furukawa Y, Yamane T, Hiyoshi M, Kishida T, Im T, Tatsumi N, Okuda K
Osaka City Med J. 1989 Jun;35(1):13-9.
Clinical outcome of fifty-one cases of non-Hodgkin's lymphoma limited to the head and neck were studied for differences with involvement of one of two sites: Waldyer's ring, and the nasal cavity and paranasal sinuses taken together. The median survival for patients with involvement of Waldyer's ring was 58.6 months, and for the other group, 10.3 months. The patients with involvement of the nasal cavity and paranasal sinuses responded poorly to treatment and the lymphoma rapidly progressed. In these patients, the lymphomas were not of the diffuse small cell type, which has a relatively good prognosis: but T cell type. The poor outcome with involvement of the nasal cavity and paranasal sinuses may be due to histological and immunological factors, and to inadequate therapy. Early combination chemotherapy might give better results for this group.
对51例局限于头颈部的非霍奇金淋巴瘤患者的临床结果进行了研究，以探讨累及Waldeyer环和鼻腔及鼻窦这两个部位之一时的差异。累及Waldeyer环的患者中位生存期为58.6个月，另一组为10.3个月。累及鼻腔及鼻窦的患者对治疗反应不佳，淋巴瘤进展迅速。在这些患者中，淋巴瘤并非预后相对较好的弥漫小细胞型，而是T细胞型。鼻腔及鼻窦受累预后不佳可能是由于组织学和免疫学因素以及治疗不足所致。早期联合化疗可能会使该组患者获得更好的结果。
