Máttyus A, Halász A
Orv Hetil. 1989 Jul 9;130(28):1493-6.
The authors report on the sleep activation of the EEG-recordings by Promazine a Phenothiazine derivative that can be used also in babies and in those elder children who does not tolerate sleep deprivation. The EEG-s are much less altered then by other related compounds or by Barbiturates. The greatest efficacy could be reached in generalized epilepsies, but the method was helpful in other epilepsy forms too. It is emphasized that in no case of acute neurological symptoms of not epileptic origin showed the Promazine induced sleep a convulsive activity.
作者报告了氯丙嗪(一种吩噻嗪衍生物,也可用于婴儿和那些不能耐受睡眠剥夺的大龄儿童)对脑电图记录的睡眠激活作用。与其他相关化合物或巴比妥类药物相比,脑电图的变化要小得多。在全身性癫痫中可达到最大疗效,但该方法对其他癫痫形式也有帮助。需要强调的是,在任何非癫痫性起源的急性神经症状病例中,氯丙嗪诱导的睡眠均未显示出惊厥活动。