Máttyus A, Halász A
Neurological Department, Heim Pál Children's Hospital, Budapest, Hungary.
Acta Paediatr Hung. 1990;30(2):317-27.
The authors report on the convulsive activity provoking effect of Promazine as shown on EEG during sleep. It has successfully been used in infants and children who do not tolerate sleep deprivation. Promazine had smaller effect on the EEG-pattern than other related compounds or barbiturates. The greatest efficacy could be reached in generalised epilepsy, but the method was also helpful in other epilepsies. It is emphasized that in cases of acute neurological symptoms of not epileptical origin the compound is helpful to exclude epilepsy since Promazine induced sleep was never associated with convulsive activity on EEG in these cases.
作者报告了氯丙嗪在睡眠期间脑电图上显示出的诱发惊厥活动的作用。它已成功用于不能耐受睡眠剥夺的婴幼儿。与其他相关化合物或巴比妥类药物相比，氯丙嗪对脑电图模式的影响较小。在全身性癫痫中可达到最大疗效，但该方法对其他癫痫也有帮助。需要强调的是，在非癫痫性起源的急性神经症状的情况下，该化合物有助于排除癫痫，因为在这些情况下，氯丙嗪诱导的睡眠从未与脑电图上的惊厥活动相关联。
