Sahdev Anju
St Bartholomew's Hospital, Barts Health, West Smithfield, London, EC1A 7BE, UK.
Cancer Imaging. 2016 Aug 2;16(1):19. doi: 10.1186/s40644-016-0076-2.
CT of the abdomen and pelvis is the first line imaging modality for staging, selecting treatment options and assessing disease response in ovarian cancer. The staging CT provides disease distribution, disease burden and is the imaging surrogate for surgico-pathological FIGO staging. Optimal cyto-reductive surgery offers patients' the best chance for disease control or cure, but sub-optimal resection confers no advantage over chemotherapy and adversely increases the risk of post surgical complications. Although there is extensive literature comparing performance of CT against laparoscopy and surgery, for the staging abdominal and pelvic CT, there are currently no accepted guidelines for interpretation or routinely used minimum data set templates for reporting these complex CT scans often with extensive radiological findings. This review provides a systematic approach for identifying the important radiological findings and highlighting important sites of disease within the abdomen and pelvis, which may alter or preclude surgery at presentation or after adjuvant chemotherapy. The distribution of sites and volume of disease can be used to categorize patients as suitable, probably suitable or not suitable for optimal cyto-reductive surgery. This categorization can potentially assist oncological surgeons and oncologists as a semi objective assessment tool useful for selecting patient treatment, streamlining multi disciplinary discussion and improving the reproducibility and correlation of CT with surgical findings. The review also highlights sites of disease and complications of ovarian cancer which should be included as part of the radiological report as these may require additional surgical input from non gynaecological surgeons or influence treatment selection.
腹部和盆腔CT是卵巢癌分期、选择治疗方案及评估疾病反应的一线成像方式。分期CT可显示疾病分布和疾病负担,是手术病理FIGO分期的成像替代指标。最佳的细胞减灭术为患者提供了控制疾病或治愈疾病的最佳机会,但次优切除与化疗相比并无优势,反而会增加术后并发症的风险。尽管有大量文献比较了CT与腹腔镜检查及手术的性能,但对于腹部和盆腔CT分期,目前尚无公认的解读指南,也没有常规使用的最小数据集模板来报告这些常有广泛影像学表现的复杂CT扫描。本综述提供了一种系统方法,用于识别重要的影像学表现,并突出腹部和盆腔内疾病的重要部位,这些部位可能会改变或排除初次就诊时或辅助化疗后的手术可能性。疾病部位和体积的分布可用于将患者分类为适合、可能适合或不适合最佳细胞减灭术。这种分类可能有助于肿瘤外科医生和肿瘤学家作为一种半客观的评估工具,用于选择患者的治疗方案、简化多学科讨论,并提高CT与手术结果的可重复性和相关性。本综述还强调了卵巢癌的疾病部位和并发症,这些应作为放射学报告的一部分,因为它们可能需要非妇科外科医生的额外手术干预或影响治疗选择。