Howes K A, Newton B W, Maley B E
Department of Anatomy and Neurobiology, University of Kentucky Medical Center, Lexington 40536.
Peptides. 1989 Jan-Feb;10(1):73-8. doi: 10.1016/0196-9781(89)90079-x.
The nucleus tractus solitarius possessed distinct patterns of cholecystokinin immunoreactive fibers and cell bodies within its various subdivisions. The commissural, medial, intermediate, parvocellular, dorsolateral and interstitial subdivisions contained relatively dense amounts of CCK immunolabelled fibers. In contrast, CCK immunoreactivity within the ventrolateral subdivision consisted of a few scattered fibers and small neurons. The commissural, intermediate, medial, dorsolateral and parvocellular subdivisions contained CCK immunoreactive neurons following colchicine treatment. The presence of CCK in the NTS suggest that it may be involved as a neuromodulator and/or neurotransmitter in circuitry that mediate cardiovascular, respiratory, gastrointestinal and taste functions.
孤束核在其各个亚区具有不同模式的胆囊收缩素免疫反应性纤维和细胞体。连合、内侧、中间、小细胞、背外侧和间质亚区含有相对密集的CCK免疫标记纤维。相比之下，腹外侧亚区内的CCK免疫反应性由一些散在的纤维和小神经元组成。连合、中间、内侧、背外侧和小细胞亚区在秋水仙碱处理后含有CCK免疫反应性神经元。孤束核中CCK的存在表明，它可能作为神经调质和/或神经递质参与介导心血管、呼吸、胃肠和味觉功能的神经回路。
