Maley B E, Panneton W M
Department of Anatomy and Neurobiology, University of Kentucky Medical Center, Lexington 40536.
Brain Res. 1988 Mar 1;442(2):340-4. doi: 10.1016/0006-8993(88)91521-1.
Enkephalin immunoreactive neurons within the nucleus tractus solitarius (NTS) were found to project to the parabrachial nucleus of the cat with the use of a combination of immunohistochemistry and retrograde transport of horseradish peroxidase. Double labelled neurons were located in the medial, parvocellular and commissural subdivisions of the NTS and were present predominantly ipsilateral to the injection site within the parabrachial nucleus. Only a few double labelled neurons were found in the contralateral NTS. The presence of neurons containing enkephalin immunoreactivity suggests that the role of enkephalin in the regulation of autonomic functions may be, in part, by circuits between the NTS and the parabrachial nucleus.
利用免疫组织化学和辣根过氧化物酶逆行运输相结合的方法，发现孤束核（NTS）内的脑啡肽免疫反应性神经元投射到猫的臂旁核。双标记神经元位于NTS的内侧、小细胞和连合亚区，主要存在于臂旁核注射部位的同侧。在对侧NTS中仅发现少数双标记神经元。含有脑啡肽免疫反应性的神经元的存在表明，脑啡肽在自主功能调节中的作用可能部分是通过NTS和臂旁核之间的回路实现的。
