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孕期母体睡眠质量与日间皮质醇调节。

Maternal Sleep Quality and Diurnal Cortisol Regulation Over Pregnancy.

机构信息

a Centers for Behavioral and Preventive Medicine , The Miriam Hospital , Providence , Rhode Island , USA.

b Department of Psychiatry and Human Behavior , Alpert Medical School of Brown University , Providence , Rhode Island , USA.

出版信息

Behav Sleep Med. 2018 May-Jun;16(3):282-293. doi: 10.1080/15402002.2016.1210147. Epub 2016 Aug 2.

Abstract

Poor sleep in pregnancy is related to adverse neonatal health. Elevated maternal cortisol has been proposed as a pathway, yet the association in pregnancy is not well understood. The goals of the current study were to examine associations between (a) sleep and cortisol, (b) sleep, cortisol, and neonatal outcomes, and (c) variables that could explain these associations. Two hundred pregnant women completed the Pittsburgh Sleep Quality Index (PSQI; Buysse, Reynolds, Monk, Berman, & Kupfer, 1989) and provided diurnal salivary cortisol samples at two times over pregnancy. Poor sleep quality was associated with greater evening cortisol concentrations at 36 weeks' gestation. This association was mediated by anxiety symptoms. Higher evening cortisol at 36 weeks' gestation was associated with shorter gestation.

摘要

孕期睡眠质量差与新生儿健康不良有关。有研究提出,母体皮质醇水平升高可能是一个影响因素,但孕期皮质醇水平与睡眠质量的关系尚不清楚。本研究的目的是探讨(a)睡眠与皮质醇,(b)睡眠、皮质醇与新生儿结局,以及(c)可以解释这些关联的变量之间的关系。200 名孕妇完成了匹兹堡睡眠质量指数(PSQI;Buysse 等人,1989 年)的评估,并在孕期的两个时间点提供了日间唾液皮质醇样本。睡眠质量差与 36 周妊娠时的傍晚皮质醇浓度升高有关。这种关联是通过焦虑症状介导的。36 周妊娠时的傍晚皮质醇水平较高与妊娠时间较短有关。

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