Spradling Philip R, Xing Jian, Rupp Loralee B, Moorman Anne C, Gordon Stuart C, Teshale Eyasu T, Lu Mei, Boscarino Joseph A, Trinacty Connie M, Schmidt Mark A, Holmberg Scott D
Division of Viral Hepatitis, Centers for Disease Control and Prevention, Atlanta, Georgia.
Clin Infect Dis. 2016 Nov 1;63(9):1205-1208. doi: 10.1093/cid/ciw516. Epub 2016 Aug 2.
Among 2338 chronic hepatitis B patients followed during 2006-2013 in the Chronic Hepatitis Cohort Study, 78% had ≥1 alanine aminotransferase and 37% had ≥1 hepatitis B virus DNA level assessed annually. Among cirrhotic patients, 46% never had hepatic imaging. Patients in this cohort were insufficiently monitored for disease activity and hepatocellular carcinoma.
在2006年至2013年慢性丙型肝炎队列研究中随访的2338例慢性乙型肝炎患者中，78%的患者每年至少有1次丙氨酸转氨酶升高，37%的患者每年至少有1次乙肝病毒DNA水平检测。在肝硬化患者中，46%从未进行过肝脏影像学检查。该队列中的患者对疾病活动和肝细胞癌的监测不足。
