杜氏肌营养不良症中肌肉力量与运动功能的关系。
Relationship between muscle strength and motor function in Duchenne muscular dystrophy.
作者信息
Nunes Milene F, Hukuda Michele E, Favero Francis M, Oliveira Acary B, Voos Mariana C, Caromano Fátima A
机构信息
Universidade de São Paulo, Faculdade de Medicina, Departamento de Fisioterapia, Fonoaudiologia e Terapia Ocupacional, São Paulo SP, Brasil;
Universidade Federal de São Paulo, Faculdade de Medicina, Departamento de Neurologia, São Paulo SP, Brasil.
出版信息
Arq Neuropsiquiatr. 2016 Jul;74(7):530-5. doi: 10.1590/0004-282X20160085.
OBJECTIVE
To investigate the relationship between muscle strength and motor function and between these variables and age.
METHOD
Muscle strength was measured by Medical Research Council (MRC) scale and motor function, by Motor Function Measure (MFM), in 40 non-ambulatory patients. Spearman tests investigated the relationships between muscle strength, motor function and age.
RESULTS
Total MRC and MFM scores were strongly related to each other (r = 0.94; p < 0.001), but not to age (r = -0.19, r = -0.31, respectively; p > 0.05). Strong and moderate relationships between partial muscle strength and motor function scores were found. Higher correlation coefficients were found between total scores and Dimensions 2 (axial/ proximal control) and 3 (distal control) of MFM.
CONCLUSION
Muscle strength and motor function are strongly correlated and seem to decrease proportionally in DMD.
目的
探讨肌肉力量与运动功能之间的关系，以及这些变量与年龄之间的关系。
方法
采用医学研究委员会（MRC）量表测量40例非行走患者的肌肉力量，采用运动功能测量（MFM）评估其运动功能。Spearman检验用于研究肌肉力量、运动功能与年龄之间的关系。
结果
MRC总分与MFM总分密切相关（r = 0.94；p < 0.001），但与年龄无关（r分别为 -0.19和 -0.31；p > 0.05）。部分肌肉力量与运动功能评分之间存在强和中度关系。总分与MFM的维度2（轴向/近端控制）和维度3（远端控制）之间的相关系数更高。
结论
肌肉力量与运动功能密切相关，在杜氏肌营养不良症（DMD）中似乎成比例下降。
Zotero 插件