Zhang Yang, Zhang Dan, Zhu Baoyu, Zhang He, Sun Ye, Sun Chengxun
Electrical Power Research Institute, Jilin Electrical Power Company Limited, Changchun 130021, China.
Electrical Power Research Institute, Jilin Electrical Power Company Limited, Changchun 130021, China.
Environ Toxicol Pharmacol. 2016 Sep;46:183-187. doi: 10.1016/j.etap.2016.07.016. Epub 2016 Jul 26.
Although it has been several decades since the focus on the effect of extremely low frequency electromagnetic fields (ELF-EMF) of high-voltage power lines on human health, no consistent conclusion has been drawn. The present study aimed to investigate the change in oxidative stress after exposure to ELF-EMFs, and potential protective effects of green tea polyphenol supplementation (GTPS) on ELF-EMFs induced oxidative stress. A total of 867 subjects, including workers with or without exposure to ELF-EMFs of 110-420kV power lines, participated and were randomized into GTPS and placebo treatment groups. Oxidative stress and oxidative damage to DNA were assessed by urinary tests of 8-isoprostane and 8-OHdG. Significant increased urinary 8-isoprostane and 8-OHdG were observed in workers with ELF-EMFs exposure, which were diminished after 12 months of GTPS. No protective effects of GTPS on oxidative stress and oxidative damage to DNA were observed after three months of GTPS withdraw. We found a negative impact of high-voltage power lines on the health of workers. Long-term GTPS could be an efficient protection against the health issues induced by high-voltage power lines.
尽管自关注高压输电线的极低频电磁场（ELF-EMF）对人类健康的影响以来已有数十年，但尚未得出一致的结论。本研究旨在调查暴露于ELF-EMF后氧化应激的变化，以及补充绿茶多酚（GTPS）对ELF-EMF诱导的氧化应激的潜在保护作用。共有867名受试者参与，包括接触或未接触110 - 420kV输电线ELF-EMF的工人，并被随机分为GTPS治疗组和安慰剂治疗组。通过尿液检测8-异前列腺素和8-羟基脱氧鸟苷评估氧化应激和DNA氧化损伤。在暴露于ELF-EMF的工人中观察到尿液中8-异前列腺素和8-羟基脱氧鸟苷显著增加，在GTPS治疗12个月后这些指标有所降低。在停止GTPS治疗三个月后，未观察到GTPS对氧化应激和DNA氧化损伤的保护作用。我们发现高压输电线对工人健康有负面影响。长期补充GTPS可能是预防高压输电线引发的健康问题的有效措施。
