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基于近红外有机染料的显著体内非线性光声成像。

Remarkable In Vivo Nonlinear Photoacoustic Imaging Based on Near-Infrared Organic Dyes.

机构信息

School of Electrical and Electronic Engineering, Nanyang Technological University, 50 Nanyang Avenue, Singapore, 639798.

Division of Chemistry and Biological Chemistry, School of Physical and Mathematical Sciences, Nanyang Technological University, 21 Nanyang Link, Singapore, 637371.

出版信息

Small. 2016 Oct;12(38):5239-5244. doi: 10.1002/smll.201602121. Epub 2016 Aug 4.

Abstract

Two near-infrared dyes featuring good dispersion and light-harvesting property present a remarkable nonlinear photoacoustic response in vitro and in vivo comparing with conventional gold nanorods. This study benefits the fabrication of drug delivery platforms with accurate targeting and control effect under photoacoustic image guidance.

摘要

两种具有良好分散性和光捕获性能的近红外染料在体外和体内表现出显著的非线性光声响应,优于传统的金纳米棒。本研究有利于在光声图像引导下制备具有精确靶向和控制效果的药物输送平台。

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