钴催化芳烃与未活化烯烃的C-H烯基化反应。
Cobalt-catalyzed C-H olefination of aromatics with unactivated alkenes.
作者信息
Manoharan Ramasamy, Sivakumar Ganesan, Jeganmohan Masilamani
机构信息
Department of Chemistry, Indian Institute of Science Education and Research, Pune 411021, India.
出版信息
Chem Commun (Camb). 2016 Aug 18;52(69):10533-6. doi: 10.1039/c6cc04835h.
A cobalt-catalyzed C-H olefination of aromatic and heteroaromatic amides with unactivated alkenes, allyl acetates and allyl alcohols is described. This method offers an efficient route for the synthesis of vinyl and allyl benzamides in a highly stereoselective manner. It is observed that the ortho substituent on the benzamide moiety is crucial for the observation of allylated products in unactivated alkenes.
描述了一种钴催化的芳香族和杂芳香族酰胺与未活化烯烃、醋酸烯丙酯和烯丙醇的C-H烯基化反应。该方法为以高度立体选择性的方式合成乙烯基和烯丙基苯甲酰胺提供了一条有效途径。据观察，苯甲酰胺部分的邻位取代基对于在未活化烯烃中观察到烯丙基化产物至关重要。
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