Marola Olivia, Cherala Rasan, Prusik Julia, Kumar Vignessh, Fama Chris, Wilock Meghan, Crimmins Jordan, Pilitsis Julie G
Department of Neurosurgery, Albany Medical Center, Albany, NY, USA.
Department of Neuroscience and Experimental Therapeutics, Albany Medical Center, Albany, NY, USA.
Neuromodulation. 2017 Apr;20(3):269-273. doi: 10.1111/ner.12482. Epub 2016 Aug 5.
Spinal cord stimulation (SCS) is an effective method of treating chronic pain. Obese patients are overrepresented in chronic pain cases. We examine the effect of body mass index (BMI) on SCS success.
We prospectively follow outcome measures including visual analog score, Beck Depression Inventory (BDI), McGill Pain Questionnaire, Oswestry Disability Index (ODI), Pain Catastrophizing Scale (PCS), and the Insomnia Severity Index at baseline, six months, and one year postoperatively. Retrospectively, we examined whether our patients with a BMI above the 75th percentile (BMI ≥36.5) had worse outcomes.
Our analysis included thoracic and cervical SCS patients-19 with a BMI ≥36.5 and 58 with a BMI <36.5. High BMI patients experienced less BDI improvement at 6 months (T(df) 2.257(36); p = 0.030; 95% CI [4.7%, 87.4%]) and one year (2.74(28); p = 0.011; 95% CI [18.1%, 125.0%]) post-SCS. High BMI patients had less improvement in pain as measured by the PCS at one year (U = 79.5; p = 0.045; 95% CI [-116.0%, 0.0%]).
Each group experienced successful surgical outcomes. High BMI patients had less BDI improvement at six months and one year and less PCS improvement at one year. These data aid us in counseling our patients preoperatively.
脊髓刺激(SCS)是治疗慢性疼痛的一种有效方法。肥胖患者在慢性疼痛病例中占比过高。我们研究了体重指数(BMI)对SCS成功率的影响。
我们前瞻性地跟踪了包括视觉模拟评分、贝克抑郁量表(BDI)、麦吉尔疼痛问卷、奥斯维斯特残疾指数(ODI)、疼痛灾难化量表(PCS)以及失眠严重程度指数等结局指标,分别在基线、术后6个月和1年进行评估。回顾性地,我们检查了BMI高于第75百分位数(BMI≥36.5)的患者是否有更差的结局。
我们的分析纳入了胸段和颈段SCS患者——19例BMI≥36.5,58例BMI<36.5。高BMI患者在SCS术后6个月(T(df) 2.257(36);p = 0.030;95% CI [4.7%, 87.4%])和1年(2.74(28);p = 0.011;95% CI [18.1%, 125.0%])时BDI改善较少。根据PCS测量,高BMI患者在1年时疼痛改善较少(U = 79.5;p = 0.045;95% CI [-116.0%, 0.0%])。
每组患者手术结局均成功。高BMI患者在6个月和1年时BDI改善较少,在1年时PCS改善较少。这些数据有助于我们在术前为患者提供咨询。