Suárez-Villanueva D, Cordero-Tous N, Paul-Ríos C, Sánchez-Corral C, Ortiz-García I M, Jouma-Katati M, Gálvez-Mateos R, Olivares-Granados G
Hospital Universitario Virgen de las Nieves, 18013 Granada, España.
Universidad de Granada, Granada, España.
Rev Neurol. 2024 Aug 16;79(4):99-105. doi: 10.33588/rn.7904.2024087.
The objective of treatment of complex regional pain syndrome is to relieve pain and restore function in the affected limb. The aim of this study is to evaluate spinal cord stimulation as a therapy for patients diagnosed with complex regional pain syndrome, for whom adequate pain control could not be achieved with other previous treatments.
A prospective study was conducted from 2018 to 2020. We included patients diagnosed with complex regional pain syndrome refractory to other treatments or techniques, classified by demographic data. Efficacy, functionality and opioid dependence in each patient were subsequently monitored for one year.
Seven of the 13 patients (53.84%) included in the study achieved significant pain relief with spinal cord stimulation. Improvements in pain and functionality were obtained, and both were statistically significant (p < 0.001 and p = 0.003, respectively). Improvement in the Oswestry Disability Index/Neck Disability Index (ODI/NDI) was significantly associated with body mass index (BMI) (p = 0.011) and was lower as BMI increased.
The results suggest that spinal cord stimulation is an effective therapeutic option for patients with CRPS refractory to other treatments. BMI and ODI/NDI also showed a significant correlation.
复杂性区域疼痛综合征的治疗目标是缓解疼痛并恢复患肢功能。本研究的目的是评估脊髓刺激作为一种治疗方法，用于那些经先前其他治疗无法实现充分疼痛控制且被诊断为复杂性区域疼痛综合征的患者。
于2018年至2020年进行了一项前瞻性研究。我们纳入了被诊断为对其他治疗或技术难治的复杂性区域疼痛综合征患者，并按人口统计学数据进行分类。随后对每位患者的疗效、功能及阿片类药物依赖情况进行了为期一年的监测。
本研究纳入的13例患者中有7例（53.84%）通过脊髓刺激实现了显著的疼痛缓解。疼痛和功能均得到改善，且两者均具有统计学意义（分别为p < 0.001和p = 0.003）。奥斯威斯利功能障碍指数/颈部功能障碍指数（ODI/NDI）的改善与体重指数（BMI）显著相关（p = 0.011），且随着BMI升高而降低。
结果表明，脊髓刺激对于对其他治疗难治的复杂性区域疼痛综合征患者是一种有效的治疗选择。BMI与ODI/NDI也显示出显著相关性。
