Ramos-Soriano Javier, Reina José J, Pérez-Sánchez Alfonso, Illescas Beatriz M, Rojo Javier, Martín Nazario
Departamento de Química Orgánica, Fac. CC. Químicas, Universidad Complutense de Madrid, Av. Complutense s/n, 28040 Madrid, Spain.
Glycosystems Laboratory, Instituto de Investigaciones Químicas (IIQ), CSIC-Universidad de Sevilla, Av. Américo Vespucio 49, 41092 Seville, Spain.
Chem Commun (Camb). 2016 Aug 18;52(69):10544-6. doi: 10.1039/c6cc05484f.
The synthesis of a new highly symmetric hexakis adduct of C60 appended with 12 cyclooctyne moieties has been carried out. This compound has been used for the copper-free strain-promoted cycloaddition reaction to a series of azides with excellent yields. This strategy for the obtention of clicked adducts of [60]fullerene is of special interest for biological applications.
已合成了一种新的高度对称的C60六加成物，其连接有12个环辛炔部分。该化合物已用于与一系列叠氮化物进行无铜应变促进的环加成反应，产率优异。这种获得[60]富勒烯点击加成物的策略在生物应用方面具有特殊意义。
