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巴西成年人艾滋病发病率的时空分析。

Spatiotemporal Analysis of AIDS Incidence Among Adults in Brazil.

作者信息

da Silva Lizzi Elisangela Aparecida, Nunes Altacilio Aparecido, Martinez Edson Zangiacomi

机构信息

Ribeirão Preto Medical School, University of São Paulo, Brazil.

出版信息

Curr HIV Res. 2016;14(6):466-475. doi: 10.2174/1570162x14666160802153025.

Abstract

UNLABELLED

AIDS is the fourth leading cause of death worldwide and, currently, the overall prevalence rate of HIV infection in Brazil is 0.5% among men and 0.3% among women.

OBJECTIVE

To evaluate the spatiotemporal trend of AIDS in Brazil from 2006 to 2012 and its relationship with human development index (HDI) and their components income, education and life expectancy.

METHODS

This ecological study evaluate the spatiotemporal trend of standardized incidence ratio of AIDS among adults in Brazil from 2006 to 2012 and its relationship with HDI by using a Bayesian analysis, considering the Brazilian Federal Units as units of analysis. The proposed statistical model allows obtaining a standardized incidence ratio (SIR, adjusted by gender and age).

RESULTS

Among the men, our results show higher incidence rates in the States of the Southern regions as well as in the state of Amazonas (Northern Brazil). In females, we found other patterns for SIR, with higher incidence rates in the states of Rio de Janeiro (Southeast region), Rio Grande do Sul and Santa Catarina (both in Southern region). Among men it was observed as an expressive association between the SIR values and the overall HDI and income and education components, but it was observed to have an inverse association with the life expectancy component. Among women, it is noted that the SIR values are associated with the overall HDI and the education components only at the beginning of the studied period.

DISCUSSION

AIDS remains a major public health problem in Brazil, mainly in the southern and southeastern regions of the country. Considering its association with HDI, it is noted that the disease still remains related to the pattern observed in the early years of the studied period, at least in the more developed regions of Brazil. This certainly happened because of the chronicity of the disease, thus affecting people with good socioeconomic status.

摘要

未标注

艾滋病是全球第四大死因,目前巴西男性艾滋病毒感染总体患病率为0.5%,女性为0.3%。

目的

评估2006年至2012年巴西艾滋病的时空趋势及其与人类发展指数(HDI)及其组成部分收入、教育和预期寿命的关系。

方法

本生态研究采用贝叶斯分析评估2006年至2012年巴西成年人艾滋病标准化发病率的时空趋势及其与HDI的关系,将巴西联邦单位作为分析单位。所提出的统计模型允许获得标准化发病率(SIR,按性别和年龄调整)。

结果

在男性中,我们的结果显示南部地区各州以及亚马孙州(巴西北部)发病率较高。在女性中,我们发现SIR有其他模式,里约热内卢州(东南部地区)、南里奥格兰德州和圣卡塔琳娜州(均在南部地区)发病率较高。在男性中,观察到SIR值与总体HDI以及收入和教育组成部分之间存在显著关联,但与预期寿命组成部分呈负相关。在女性中,注意到SIR值仅在研究期开始时与总体HDI和教育组成部分相关。

讨论

艾滋病在巴西仍然是一个主要的公共卫生问题,主要在该国南部和东南部地区。考虑到其与HDI的关联,注意到该疾病仍然与研究期早期观察到的模式相关,至少在巴西较发达地区如此。这肯定是由于该疾病的慢性,从而影响了社会经济地位良好的人群。

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