Wiswedel K, North C, Baillie P
Department of Obstetrics and Gynaecology, University of Cape Town.
S Afr Med J. 1989 Jul 15;76(2):70-1.
A 38-year-old nulliparous woman suffering from premature menopause was stimulated with oestradiol valerate in order to create an artificial endometrial cycle. Three oocytes were donated by a woman on an in vitro fertilisation cycle and were inseminated with the patient's husband's sperm. These were then transferred into the patient's uterus after the endometrium had been primed with progesterone to change it to the secretory phase. Pregnancy resulted and proceeded well. Gestation was terminated at the 34th week by caesarean section and 2 healthy boys and 1 girl were delivered.
一名38岁未生育且患有过早绝经的女性,为了建立人工子宫内膜周期,接受了戊酸雌二醇刺激。三名卵母细胞由一名处于体外受精周期的女性捐赠,并与患者丈夫的精子进行受精。在子宫内膜用孕酮预处理转变为分泌期后,将这些胚胎移植到患者子宫内。成功受孕且进展顺利。妊娠在第34周通过剖宫产终止,产下2名健康男婴和1名女婴。