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[硫化氢中毒与神经系统损伤]

[H2S poisoning and nervous system damage].

作者信息

Tvedt B, Skyberg K, Aaserud O, Edland A, Hobbesland A, Mathiesen T

出版信息

Tidsskr Nor Laegeforen. 1989 Jun 30;109(19-21):2007-11.

PMID:2749690
Abstract

H2S (hydrogen sulfide) is a very toxic gas. Even brief exposure to high concentrations may be fatal. Unconsciousness may occur without warning. Those who try to help are often poisoned too. In Norway, most poisonings have been described in connection with the herring oil and fish meal industry, farmers handling manure, and sewage work. The risk of hypoxic damage to the nervous system is considerable. The clinical picture varies, and the connection between the patients' symptoms and the poisoning is easily overlooked, especially with delayed sequelae, which may occur several weeks after the acute poisoning. The risk of damage depends on both the exposure time and the concentration of H2S, and a thorough anamnesis, noting the course of events, is important in order to achieve a correct diagnosis.

摘要

硫化氢(H2S)是一种剧毒气体。即使短时间暴露于高浓度环境中也可能致命。可能会在毫无预警的情况下失去意识。试图施救的人也常常会中毒。在挪威,大多数中毒事件都与鲱鱼油和鱼粉行业、处理粪便的农民以及污水处理工作有关。神经系统发生缺氧性损伤的风险相当大。临床表现各不相同,患者症状与中毒之间的关联很容易被忽视,尤其是对于急性中毒数周后可能出现的迟发性后遗症。损伤风险取决于暴露时间和硫化氢浓度,为了做出正确诊断,详细记录事件经过的全面问诊非常重要。

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